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BioLife Solutions HypoThermosol(R) Adopted by MicroIslet for Processing Pancreatic Islet Cells to Treat Diabetes
Date:10/24/2008

very of the islets processed after using HypoThermosol as a cold storage solution for a duration of 24-27 hours was significantly improved and consisted of a viability range of 80%-90%, compared to an average of 50%-65% viability when pancreata were stored in previously tested solutions. Furthermore, the necrotic and apoptotic cell death profiles of islets from pancreata stored in HypoThermosol were similar to those typically seen for islets from fresh pancreata.

BioLife Chairman and Chief Executive Mike Rice remarked: "We're quite pleased to be supporting MicroIslet's efforts to develop and commercialize a cure for diabetes. This is yet another example of how our products improve the viability of cells and tissue throughout the hypothermic storage and thawing processes and significantly increase tissue survival rate, or yield. By substantially improving yield of source material and finished products, our proprietary technology enables greater cost-effectiveness in the commercialization of new clinical therapies."

About MicroIslet:

MicroIslet is a biotechnology company engaged in the research, development, and commercialization of patented technologies in the field of cell therapy for patients with insulin-dependent diabetes. MicroIslet has licensed several technologies from Duke University for isolation, culturing, storage, and microencapsulation of insulin-producing islet cells from porcine sources. The Company believes that these technologies, and other proprietary methods developed in-house, are significant advances in the field of cellular therapeutics. MicroIslet is planning human clinical trials in the U.S., and exploring possible trials abroad. MicroIslet's ultimate goal is to offer cell transplantation therapies for diabetic patients worldwide.

The Company's lead product, MicroIslet-PTM, consists of microencapsulated porcine islets for implantation into the abdominal cavity using a minimally invasive procedure. Microencapsulation
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SOURCE BioLife Solutions Inc.
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