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BioLife Solutions HypoThermosol(R) Adopted by MicroIslet for Processing Pancreatic Islet Cells to Treat Diabetes
Date:10/24/2008

Preservation with BioLife's Proprietary, Next Generation, Biopreservation Media Resulted in Increased Yield and Quality of Insulin-Producing Islet

Cells

BOTHELL, Wash., Oct. 24 /PRNewswire-FirstCall/ -- BioLife Solutions Inc. (OTC Bulletin Board: BLFS), a leading developer and marketer of proprietary hypothermic storage and cryopreservation media products for cells, tissues, and organs, today announced that MicroIslet Inc. (OTC Bulletin Board: MIIS), a biotechnology company engaged in developing and commercializing cellular therapies for patients with diabetes, has adopted HypoThermosol for preserving, transporting, and storing pancreatic source material. MicroIslet plans to isolate and encapsulate islet cells for the treatment of Type 1 diabetic patients under a planned investigational new drug application and subsequent clinical trial.

Michael J. Andrews, MicroIslet's President and Chief Executive Officer, said: "Insulin-producing islet cells hold great promise in the search for a cure for Type-1 diabetes, from which 1.4 million Americans suffer. However, islet cells are fragile, and their health and quality are highly dependent on the preservation media used to store and ship the source organ. We compared HypoThermosol to several commercially available media as well as a modified two-layer method. When organs were stored in HypoThermosol there was significant improvement in the appearance of the tissues and the yield of healthy islet cells."

Dr. Ingrid Stuiver, Senior Director of Research at MicroIslet, reported to BioLife that with HypoThermosol, quality islets could still be successfully isolated from the stored organ even after a transport time of 24-27 hours. Isolation efficiency, a measure of the quantity of islet cells available from a given volume of tissue, was higher than all other shipping media tested. Viability of the isolated tissue was one of the most important criteria tested. The reco
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SOURCE BioLife Solutions Inc.
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