Navigation Links
Best Practices for Optimizing Dose Escalation in First in Human Studies, New Webinar August 6th Hosted by Xtalks
Date:7/24/2014

Toronto, Canada (PRWEB) July 24, 2014

The first part of the session on “Best Practices for Optimizing Dose Escalation in First in Human Studies” will cover comprehensive clinical support in early phase studies to make better go/no-go decisions.

With increasing R&D costs and declining industry success in getting products to market, pharmaceutical companies need to maximize the knowledge collected in early Phase I/IIa study data to make better go/no-go decisions and improve success in late stage development.

Next, the presenters will examine steps to improve your dose selection and ultimately the value of your early clinical data. Using illustrative scenarios, they will explore key protocol design considerations along with essential pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation techniques.

Identifying the best dose escalation scheme in FIH studies is a critical and often underestimated step in early development decision-making. Likewise, setting up ideal study collection procedures is key to getting the most out of the subject data to efficiently produce an accurate understanding of your compound’s strengths and susceptibilities.

John the presenters, Dr. Seth Berry, Director, Clinical PK/PD Modeling & Simulation, & Center for Statistics in Drug Development at Quintiles, and Professor Tim Mant, Vice President, Medical Research and Principal Investigator at Quintiles, as they examine ways to:

  •     Optimize FIH study design from sampling plans to adjusting dose escalation based on tolerability and PK-PD during the course of the study for the most efficient and effective strategy
  •     Use PK-PD modeling and simulation to guide dosing for each cohort

Viewers will gain an understanding of ways to make the most of your early clinical development -- from efficiently conducting
'/>"/>

Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. All eligible Texas Childrens Pediatrics practices receive highest Patient Centered Medical Home Recognition from the National Committee for Quality Assurance
2. Certified Scrum Product Owner Training by Lonnie Weaver-Johnson in Richmond by Conscires Agile Practices
3. Best Practices in Patient Recruitment and Retention for Diabetes Trials, New Life Science Webinar Hosted by Xtalks
4. Key Findings from Social Media and Email Best Practices Guide for Marketing to Life Scientists
5. BioInformatics, LLC New Market Research Report – Social Media and Email Best Practices Guide for Marketing to Life Scientists
6. SCAI Paper Highlights Best Practices For Diagnosing And Treating Blocked Arteries Via The Wrist
7. Agile and Scrum Workshop – Values, Foundations, and Practices in San Diego, CA by Conscires Agile Practices
8. “Agile and Scrum – Values, Foundations, and Practices” in Philadelphia, PA- 8 PDUs
9. Affordable Pay It Forward Agile & Scrum Training Richmond, VA in by Conscires Agile Practices on Sept. 20
10. Affordable Scrum Training in London, UK on October 7th 2013 by Conscires Agile Practices
11. Announcing a Certified ScrumMaster Training on September 19-20, 2013 – 14 PDUs in Denver, CO by Conscires Agile Practices
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... Ipsen Biopharmaceuticals, Inc., an affiliate ... IPSEY), today announced that Somatuline® Depot® (lanreotide) ... approved by the U.S. Food and Drug Administration ... (GEP-NETs) in adult patients with unresectable, well or ... improve progression-free survival (PFS). , “The approval of ...
(Date:12/17/2014)... This report is a professional and ... an overview analysis, the report introduces quartz tubing ... industry overview, policy analysis, and news analysis, etc. ... witnessed rapid development with key manufacturers increasing their ... mentions quartz tubing upstream raw materials and equipment, ...
(Date:12/17/2014)... Gene synthesis and bioengineering company ... into a technology access and services agreement with ... proprietary protein engineering technology, known as “ProteinGPS®” to ... extremely excited that the global leader ADM has ... bioengineering technology has now been validated through many ...
(Date:12/17/2014)... 16, 2014  Vermillion, Inc. (NASDAQ: VRML ... today announced the next step in its expanded strategy ... provider with the naming of current Chief Operating Officer, ... Officer, while current Chairman of the Board and CEO ... Chairman. These changes are effective January 1, 2015. ...
Breaking Biology Technology:Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 5Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 6Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 7Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 82020 Quartz Tubing Market: Global Development & Forecasts Analysis Now at DeepResearchReports.com 2ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 3Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 4
... Halozyme Therapeutics, Inc. (Nasdaq: HALO ... targeting the extracellular matrix for the endocrinology, oncology, ... of $5.5 million from Baxter Healthcare Corporation representing ... terms of its HYLENEX licensing agreement, which provides ...
... ST. JOSEPH, Mich., Jan. 6 GeneGo, Inc., ... curated databases for systems biology,and pathway analysis ... has,renewed its MetaCore licenses for another three years. ... diseases and gynecological therapies,and GeneGo has good coverage ...
... 6 WuXi AppTec, the operating company of WuXi ... and development outsourcing company with operations in China and ... from ThalesNano Inc. for laboratory-based hydrogenation. WuXi joins ... have introduced and adopted the H-Cube technology. , ...
Cached Biology Technology:GeneGo Renews Its Agreement With Bayer Schering Pharma AG for Another Three Years 2WuXi AppTec Selects H-Cube from ThalesNano for Laboratory-based Hydrogenation 2
(Date:12/3/2014)... , Dec. 2, 2014   Marvin Test ... innovative test solutions for military, aerospace, and manufacturing ... of its successful TS-900 PXI semiconductor test ... features of high-end systems to customers at a ... compared to traditional ATE. "Our ...
(Date:11/21/2014)... NEW YORK , Nov. 19, 2014  Earlier ... Board at New York College, and one of the ... for biosensor signals that are transmitted from Smartphones to ... there were Smartphones and has one of the earliest ... are discussing its usage in the military, child care, ...
(Date:11/21/2014)... Calif. , Nov. 20, 2014   Atmel® ... leader in microcontroller (MCU) and touch technology solutions, today ... temperature sensors with the widest V cc ... higher temperature accuracy and faster I 2 C bus ... and serial EEPROM memory making them ideal for consumer, ...
Breaking Biology News(10 mins):Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 2Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 3Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 4
... Increased summer precipitation apparently helping to spread spores of ... pines in northwestern British Columbia present strong evidence in ... to blame for the outbreak. The blight, caused by ... needles and, in the case of the British Columbia ...
... adult brain can reorganize neural pathways in response to ... and responses of neurons. But it has remained an ... In a new study published in the open-access journal ... continuous monitoring of neurons in the mouse adult visual ...
... the Fungal Research Trust have discovered millions of fungal ... , Aspergillus fumigatus, the species ... to cause disease; and the resulting condition Aspergillosis has ... and bone marrow transplant patients. Fungi also exacerbate asthma ...
Cached Biology News:A new window into structural plasticity in the adult visual cortex 2Pillows - a hot bed of fungal spores 2
... Do you need to make your ... transformation efficiency? Take advantage of Lucigen’s unrivalled ... Custom Competent Cell Service offers: ... transformation efficiencies Fast turnaround ...
... products ATP-Free using Mo Bio luciferase assay. Mo ... service that will allow you to certify your ... and enable you to deliver them to your ... ATP detection limit is 3.5 x 10-12 /l, ...
Glucagon-like peptide-1 (GLP-1 (1-36) amide)...
... 'A New Concept in Microarrays: Biomedical ... chip technologies GmbH (Jena, Germany) have collaborated ... new CLONDIAG ArrayTube System. The DNAscope ... technology. The new DNAscope AT automatically reads ...
Biology Products: