Navigation Links
Best Practices for Optimizing Dose Escalation in First in Human Studies, New Webinar August 6th Hosted by Xtalks
Date:7/24/2014

Toronto, Canada (PRWEB) July 24, 2014

The first part of the session on “Best Practices for Optimizing Dose Escalation in First in Human Studies” will cover comprehensive clinical support in early phase studies to make better go/no-go decisions.

With increasing R&D costs and declining industry success in getting products to market, pharmaceutical companies need to maximize the knowledge collected in early Phase I/IIa study data to make better go/no-go decisions and improve success in late stage development.

Next, the presenters will examine steps to improve your dose selection and ultimately the value of your early clinical data. Using illustrative scenarios, they will explore key protocol design considerations along with essential pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation techniques.

Identifying the best dose escalation scheme in FIH studies is a critical and often underestimated step in early development decision-making. Likewise, setting up ideal study collection procedures is key to getting the most out of the subject data to efficiently produce an accurate understanding of your compound’s strengths and susceptibilities.

John the presenters, Dr. Seth Berry, Director, Clinical PK/PD Modeling & Simulation, & Center for Statistics in Drug Development at Quintiles, and Professor Tim Mant, Vice President, Medical Research and Principal Investigator at Quintiles, as they examine ways to:

  •     Optimize FIH study design from sampling plans to adjusting dose escalation based on tolerability and PK-PD during the course of the study for the most efficient and effective strategy
  •     Use PK-PD modeling and simulation to guide dosing for each cohort

Viewers will gain an understanding of ways to make the most of your early clinical development -- from efficiently conducting
'/>"/>

Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. All eligible Texas Childrens Pediatrics practices receive highest Patient Centered Medical Home Recognition from the National Committee for Quality Assurance
2. Certified Scrum Product Owner Training by Lonnie Weaver-Johnson in Richmond by Conscires Agile Practices
3. Best Practices in Patient Recruitment and Retention for Diabetes Trials, New Life Science Webinar Hosted by Xtalks
4. Key Findings from Social Media and Email Best Practices Guide for Marketing to Life Scientists
5. BioInformatics, LLC New Market Research Report – Social Media and Email Best Practices Guide for Marketing to Life Scientists
6. SCAI Paper Highlights Best Practices For Diagnosing And Treating Blocked Arteries Via The Wrist
7. Agile and Scrum Workshop – Values, Foundations, and Practices in San Diego, CA by Conscires Agile Practices
8. “Agile and Scrum – Values, Foundations, and Practices” in Philadelphia, PA- 8 PDUs
9. Affordable Pay It Forward Agile & Scrum Training Richmond, VA in by Conscires Agile Practices on Sept. 20
10. Affordable Scrum Training in London, UK on October 7th 2013 by Conscires Agile Practices
11. Announcing a Certified ScrumMaster Training on September 19-20, 2013 – 14 PDUs in Denver, CO by Conscires Agile Practices
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... , CA (PRWEB) , ... July 30, 2015 ... ... the successful completion of a field clinical study of its canine osteoarthritis stem ... together with Aratana Therapeutics (Kansas City, KS) and will be marketed in the ...
(Date:7/30/2015)... -- HIGHLIGHTS:Q2 2015 Results (all changes are ... sales were $697 million compared to $701 million in ... 8%, and changes in foreign currency exchange rates decreased ... , By business unit, organic sales growth was ... SAFC Commercial. , Reported diluted EPS was $0.98 ...
(Date:7/29/2015)... Sanofi, un leader mondial ... pour le premier semestre 2015. Le Directeur Général ... Visionner l,interview vidéo et lire la transcription ... Au sommaire de l,interview :  - ... - Diabète - Praluent ...
(Date:7/29/2015)...  HealthSouth Corporation (NYSE: HLS ), ... healthcare services, offering both facility-based and home-based post-acute ... the second quarter ended June 30, 2015. ... volume growth in both segments and an 11.0% ... President and Chief Executive Officer of HealthSouth. "While ...
Breaking Biology Technology:VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 3Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 2Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 3Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 4Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 5Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 6Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 7Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 8Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 9Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 10Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 11Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 12Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 13Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 14Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 15Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 16Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 17Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 18Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 19Sigma-Aldrich (NASDAQ - SIAL) Reports Q2 2015 Sales Of $697 Million And Adjusted Diluted EPS Of $1.01 20HealthSouth Reports Results for Second Quarter 2015 2HealthSouth Reports Results for Second Quarter 2015 3HealthSouth Reports Results for Second Quarter 2015 4HealthSouth Reports Results for Second Quarter 2015 5HealthSouth Reports Results for Second Quarter 2015 6HealthSouth Reports Results for Second Quarter 2015 7HealthSouth Reports Results for Second Quarter 2015 8HealthSouth Reports Results for Second Quarter 2015 9HealthSouth Reports Results for Second Quarter 2015 10HealthSouth Reports Results for Second Quarter 2015 11HealthSouth Reports Results for Second Quarter 2015 12HealthSouth Reports Results for Second Quarter 2015 13HealthSouth Reports Results for Second Quarter 2015 14HealthSouth Reports Results for Second Quarter 2015 15
... Myriant Technologies LLC (Myriant), a privately-held, biotech developer ... of its Science Advisory Board and the appointment ... collectively will provide broad insight into all aspects ... biomass feedstocks into valuable chemicals. , (Logo: ...
... ... capture investors, interest. , ... Miami, FL (PRWEB) October 21, 2009 -- iLife Americas, LLC, a leading developer ... U.S. to market its line of iLife wellness and therapeutic products. Officially opened on ...
... /PRNewswire-Asia-FirstCall/ -- China Medical Technologies,Inc. (the "Company") (Nasdaq: CMED ... markets advanced in-vitro diagnostic,products, today announced that it will attend ... to October 31, 2009 in Chengdu,China. , , ... 62nd China International Medical Equipment Fair, Date: ...
Cached Biology Technology:Myriant Technologies LLC Announces Appointment of Science Advisory Board Members 2Myriant Technologies LLC Announces Appointment of Science Advisory Board Members 3iLife Americas, LLC Enters U.S. Wellness and Therapeutic Markets 2China Medical Technologies to Exhibit its Products at China International Medical Equipment Fair in Chengdu, China 2
(Date:7/8/2015)... , July 8, 2015  Trovagene, Inc. (NASDAQ: ... diagnostics, today announced the launch of a study ... Precision Cancer Monitoring℠ (PCM) technology for predicting response ... or a combination of the novel immunotherapy agents ... a PD-1 inhibitor. The 50-patient study will be ...
(Date:7/7/2015)... July 7, 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... growing mobile commerce market announces a revised version of one of ... commercial will air on CNBC in New York ... and San Francisco metro areas.    ... on Wocket,s ability to replace all the cards in your wallet ...
(Date:6/30/2015)... 30, 2015 To bolster its efforts and commitment ... announced today the addition of two new team members. ... advisor and David Raviv will act as head ... Corp.,s commitment to providing the most secure solutions for the ... co-founded Layer 7 Technologies, a provider of security and management ...
Breaking Biology News(10 mins):Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 2Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 3Trovagene Initiates Study to Monitor Response to Immunotherapy in Melanoma Patients Using its Precision Cancer Monitoring Platform 4Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 2Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 3HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 2HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 3
... 17 October 2008 Singapore,s Prime Minister Lee Hsien ... technology and business to celebrate the opening of Fusionopolis, ... hub, Biopolis, opened five years ago. ... six phases, is the country,s icon for research in ...
... Property Inventory for Biometric Identity Management ... ... International,Inc. (OTC Bulletin Board: BKYI), a leader in finger-based biometric,identification and ... has approved the issuance of a patent for the,company,s "Biometric Identification ...
... gases from volcanic eruptions could have given rise to the ... samples from a classic origin-of-life experiment by NASA and university ... in Science appearing October 16. "Historically, you ... these; they re-defined our thoughts on the origin of life ...
Cached Biology News:Singapore opens Fusionopolis, its second major R&D hub in 5 years 2Singapore opens Fusionopolis, its second major R&D hub in 5 years 3Singapore opens Fusionopolis, its second major R&D hub in 5 years 4BIO-key(R) Granted Additional Patent for Biometric Security Solution 2BIO-key(R) Granted Additional Patent for Biometric Security Solution 3Volcanoes may have provided sparks and chemistry for first life 2Volcanoes may have provided sparks and chemistry for first life 3
... The Fujifilm Life Science FLA-5100 imaging ... samples as large as 40 x 46cm ... 10 microns. This system is especially suitable ... and general array analysis for genomics., Fuji ...
... The new FLA-5000 imaging system ... radioisotopic samples as large as ... as low as 25 microns. ... for protein electrophoresis in the ...
... The Caliper Sciclone ALH 3000 workstation automates ... applications, from Genomic and Proteomic Sample Preparation ... The modular design of the Caliper ... and accessories to perfectly meet the needs ...
Designed for use with the Agencourt SprintPrep 384 kit and all MCPrep reagent kits. Used with flat bottom 96-well microplates such as deep well plates used to culture bacteria....
Biology Products: