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BellBrook Labs Seeking Partners to Accelerate Commercialization of Innovative HTS Assay Technologies
Date:11/20/2013

ven the most non-adherent cells. Prototypes have been tested at Pharma and life science research companies, and are ready for final design optimization and full scale manufacturing.

BellBrook’s RGScreen assay is the only HTS -ready assay method for measuring Regulaor of G Protein Signaling (RGS) protein catalytic activity. The most direct way to detect RGS function is by measuring the increased GTPase activity of the associated Galpha protein. However, the GTPase activity of isolated Galpha proteins is limited by GDP dissociation, so RGS GAP activity cannot be measured using simple biochemical assays. Bellbrook’s novel RGScreen™ platform overcomes this kinetic constraint by using proprietary Galpha protein variants with altered GTP hydrolysis and GDP dissociation rates that enable detection of RGS GAP activity using the Transcreener® GDP Assay.

About BellBrook Labs. BellBrook Labs is a private, R&D driven company dedicated to accelerating drug discovery and biological research by providing innovative high throughput screening solutions for enzymes and phenotypic assays. The company’s products, including Transcreener® HTS enzyme assays and iuvo™ Microconduit Array plates are used by all of the major pharmaceutical companies and are available directly from BellBrook Labs or from their international distribution partners. For more information on any of these technologies or to discuss partnering opportunities, contact BellBrook Labs: @info.bellbrooklabs.com.

Read the full story at http://www.prweb.com/releases/2013/11/prweb11345539.htm.


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