Navigation Links
Baxter Adds Recombinant Protein to Specialty Therapeutics Portfolio
Date:10/16/2007

Agreement with Kaketsuken targets rare blood disorders

DEERFIELD, Ill., Oct. 16 /PRNewswire-FirstCall/ -- Baxter International Inc. (NYSE: BAX) today announced it has signed an agreement with Kaketsuken, the Chemo-Sero-Therapeutic Research Institute, based in Kumamoto Japan, for the worldwide rights to develop, manufacture and market the recombinant protein ADAMTS13. The development of recombinant ADAMTS13, a bio-engineered version of a naturally occurring enzyme that plays a critical role in blood coagulation, will strengthen Baxter's pre-clinical research and development pipeline for specialty therapeutics targeting rare diseases. In the absence of ADAMTS13 in the blood, patients develop a severe, often life-threatening condition called thrombotic thrombocytopenic purpura (TTP), marked by the formation of platelet-rich blood clots in blood vessels throughout the body. Recombinant ADAMTS13 is being developed for the treatment of TTP and related disorders and will be evaluated for other indications in the future. This agreement provides an opportunity for Baxter to exclusively develop a new recombinant protein and investigate its potential use in treating unmet medical needs.

"We are very excited to add recombinant ADAMTS13 to our development pipeline," said Hartmut J. Ehrlich, M.D., vice president of Global Research and Development for Baxter's BioScience business. "Elucidating the role of recombinant ADAMTS13 in TTP and other blood-clotting disorders might provide us with a new treatment modality for thrombotic diseases, which is a substantial addition to our R&D pipeline."

When a blood vessel is injured, a platelet plug is formed that adheres to the injury site and reduces or stops the blee
'/>"/>

SOURCE Baxter International Inc.
Copyright©2007 PR Newswire.
All rights reserved

2

GOOD

Page: 1 2 3 4

Related biology technology :

1. Expression and Purification of Recombinant Proteins That Have Native Amino Acid Sequence
2. Proteinase K, Recombinant, PCR Grade: the Ideal Tool for Template Preparations
3. Recombinant HIV Reverse Transcriptase
4. Purification of Recombinant Flavonone 3beta-Hydroxylase Using Bio-Scale CHT5-1 Hydroxyapatite Column
5. Preparative SDS-PAGE Electrophoresis of a Recombinant Epstein-Barr Virus Encoded Protein and Its Application in Serodiagnostic Test Systems, Rev C
6. Cell lines expressing recombinant aequorin and a G-protein coupled receptor for functional screening
7. Luciferase Reporter Gene Cells and Recombinant Luciferase Dilutions Studied with the CLIPR Luciferase Assay Kit and the LMax Microplate Luminometer (MaxLine Application Note #38)
8. A New C-Terminal GST Vector for Protein Production in S. pombe
9. New Mammalian Two-Hybrid System Detects Protein-Protein Interactions
10. Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling
11. Simple, Sensitive, and Rapid Detection of FLAG -Tagged Fusion Proteins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... BioTrends Research Group, one of the ... biopharmaceutical issues, finds that, unaided, one in five ... that in the past six months, they have ... anticipation of the next generation of HCV treatments—notably ... 6 percent reported that they had begun warehousing ...
(Date:5/23/2013)... Z Trim Holdings, Inc. (OTC Markets: ZTHO), ... of industries, announced that Chef Erin Ryan ... year,s National Restaurant Association ("NRA") NRA Show, which was ... Research Chefs Association.  Chef Ryan spoke on the subject ... and the Ugly," joining four other prestigious panelists including: ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 The New ... STEM industries, Black Data Processing Associates (BDPA), is hosting ... June 8, 2013. This all-day event will encourage students ... learn the ins and outs from many of the ... p.m. at the New Jersey Institute of Technology, the ...
(Date:5/23/2013)... SAN DIEGO , May 23, 2013  Verenium ... biotechnology company focused on the development and commercialization of ... , Chief Financial Officer, will present at two ... Mr. Black will present at the Second Annual ... at the Grand Hyatt Hotel in New York City.  ...
Breaking Biology Technology:The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 3Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 2Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 3Black Data Processing Associates (BDPA) New Jersey Hosts 10th Annual Families in Technology Day June 8, 2013 2Verenium To Present At Two Upcoming Conferences 2Verenium To Present At Two Upcoming Conferences 3
... /PRNewswire-Asia-FirstCall/ -- Yongye Biotechnology International, Inc. (OTC Bulletin Board: ... and distributor of nutrients for plants and animals, located ... the Company,s management will host a conference call and ... overview of the Company followed by a question and ...
... more than 40 years, marking second FDA approval ... Japan, Feb. 13 Takeda Pharmaceutical Company Limited ... Inc., announced today that the United States Food ... 40 mg and 80 mg for the chronic ...
... DNA testing technology provided by GeneSeek Inc.LINCOLN, Neb., ... will be used for medical-grade source pigs which ... Minnesota non-profit organization providing pig islet cells for ... a certified Illumina CSPro laboratory and global leader ...
Cached Biology Technology:Yongye Biotechnology to Host 'Virtual Retail Road Show' to Provide Overview of the Company in English and Mandarin 2Yongye Biotechnology to Host 'Virtual Retail Road Show' to Provide Overview of the Company in English and Mandarin 3Yongye Biotechnology to Host 'Virtual Retail Road Show' to Provide Overview of the Company in English and Mandarin 4FDA Approves ULORIC(R) (febuxostat) for the Chronic Management of Hyperuricemia in Patients with Gout 2FDA Approves ULORIC(R) (febuxostat) for the Chronic Management of Hyperuricemia in Patients with Gout 3FDA Approves ULORIC(R) (febuxostat) for the Chronic Management of Hyperuricemia in Patients with Gout 4Pigs to Be Genotyped to Improve Selection and Breeding for Pancreatic Islet Cell Research 2Pigs to Be Genotyped to Improve Selection and Breeding for Pancreatic Islet Cell Research 3
(Date:5/23/2013)... surgery or harsh treatments because science fails to ... of the disease. Researchers at Case Western Reserve ... technology that allows patients to safely choose to ... take drastic measures. , The project is one ... biomedical engineering at Case Western Reserve and director ...
(Date:5/23/2013)... fastest growing open-access publishers, announces the launch of ... Biotechnology . , A broad scope journal ... Biotechnology will provide a single open-access platform ... to be disseminated and discussed. , ... an open-science and interactive web platform for the ...
(Date:5/22/2013)... conclude that the 20 percent reduction in lung ... chest X-ray (CXR) screening previously reported in the ... centers in the United States. , Philadelphia, PAPhysicians ... about the benefits and risks of LDCT lung ... New England Journal of Medicine of the ...
Breaking Biology News(10 mins):Using big data to identify prostate cancers and best treatments 2Using big data to identify prostate cancers and best treatments 3Frontiers launches new open-access journal in Bioengineering and Biotechnology 2NLST: CT detects twice as many lung cancers as X-ray at initial screening exam 2NLST: CT detects twice as many lung cancers as X-ray at initial screening exam 3
... riparian willow warblers and beaver dams once were bountiful in ... once wolves left this area, elk grew more plentiful, browsing ... beavers, and sparrows have replaced the warblers in what is ... the absence of the wolf, a top predator. That's the ...
... on the rise, there is growing interest in maintaining the ... study released this week in the on-line edition of the ... a crucial role in determining how much carbon these natural ... to provide other crucial ecosystem services such as preventing erosion. ...
... tiny flatworm best known for its extraordinary ability to regenerate ... ability of stem cells to differentiate into specialized cells. The ... protein PIWI, an important regulator of stem cells in organisms ... tissue lost to injury or shed during the body's normal ...
Cached Biology News:Wolves' top-down effect 2Seeing the forest and the trees 2Regenerating worms help elucidate stem cell biology 2Regenerating worms help elucidate stem cell biology 3Regenerating worms help elucidate stem cell biology 4
... System provides a simple, rapid and ... glutathione-S-transferase (GST) fusion proteins. Immobilized glutathione ... to isolate GST-tagged protein directly from ... either a manual (requires use of ...
... Useful for the mechanical harvesting of ... and ensures even contact with the growth ... and 75cm flasks • Individually wrapped • ... Linkage: This CLS number is a new ...
... Assay Kits are ideal for studying ... compounds using fluorescence polarization (FP) The ... glutathione transferase to the ligand binding ... and a proprietary, fluorescently-tagged progesterone ligand, ...
... base (YNB) is a base medium for preparation ... contains ammonium sulfate but does not contain amino ... available. Each pouch contains reagents to prepare ... or 1000 ml of 10X YNB for S. ...
Biology Products: