Navigation Links
Basic Scientist Mark Roth Wins MacArthur Fellowship
Date:9/25/2007

a better place. They are people who will change and influence our times."

Roth's work has led to major advances in basic biology, some of which have tremendous potential for human health. In particular, his research on induced metabolic hibernation, in which he has reversibly reduced the core temperature of mice to 10 degrees Celsius without loss of life or neurological problems, could one day lead to major breakthroughs for a host of human ills caused by tissue damage from a lack of oxygen.

"Mark is an exceptionally creative and innovative scientist who has pursued successfully more original avenues of research than anyone I know," said Roth's colleague Mark Groudine, M.D., Ph.D., a member of the Basic Sciences Division and deputy director of the Hutchinson Center. "In all cases, his rare ability to identify a seemingly intractable problem and tackle it with unswerving focus -- even when it required him to learn a completely new field, establish new collaborations, challenge conventional wisdom or develop new technology -- has led to major advances in basic biology, some of which have tremendous potential for human health. In particular, his new research on metabolic flexibility could lead to major breakthroughs in the treatment of stroke, trauma and cancer."

To help move this work forward into the clinical setting, Roth in 2005 founded a Seattle biotechnology company called Ikaria Inc., which earlier this year merged with INO Therapeutics to become Ikaria Holdings, a leader in the development of therapeutic gases for use in critical-care medicine. The company, based in Clinton, N.J., also operates a research and development facility in Seattle.

Earlier this year Roth received the 2007 Award for Significant Technical Achievement by the Defense Advanced Research Projects Agency, or DARPA, a major supporter of his work, for developing technology that "could dramatically improve the survival rate of wounded fighters and provide revolutionary i
'/>"/>

SOURCE Fred Hutchinson Cancer Research Center
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Basic Plasmid DNA Isolation Protocol
2. Basic Plasmid DNA Isolation Protocol
3. Array Analysis: The Basics
4. Northern Analysis: The Basics
5. Nuclease Protection Assays: The Basics
6. TSKgel ODS-100Z and TSKgel ODS-100V column series provides a universal solution for the analysis of samples containing acidic, basic, polar & non-polar compounds
7. FERMENTATION BASICS
8. UW computer scientists fighting computer virus "Cold War"
9. UW scientist, former WiCell director found stem cell company
10. Scientists find way to make human collagen in lab
11. Wisconsin scientists to be recognized for innovative biofuel technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... 2014 Regulus Therapeutics Inc . (NASDAQ: ... discovery and development of innovative medicines targeting microRNAs, today ... for the quarter ended June 30, 2014 on Wednesday, ... Regulus will host a conference call ... pm Eastern Daylight Time to discuss its second quarter ...
(Date:7/30/2014)... TARRYTOWN, N.Y. and PARIS ... REGN) and Sanofi (EURONEXT: SAN and NYSE: SNY) today ... Food and Drug Administration (FDA) rare pediatric disease priority ... (BLA) submission for alirocumab.  The priority review voucher entitles ... which provides for an expedited 6-month review from the ...
(Date:7/30/2014)... July 30, 2014 W. R. ... release of the REVELERIS® Prep purification system ... preparative chromatographers, and other researchers to perform both ... single unit. , With the REVELERIS® Prep purification ... preparative chromatography modes with a simple touch of ...
(Date:7/30/2014)... , July 30, 2014  Decision Resources Group ... medical directors in the United States ... biosimilar market penetration will be the level of ... and the expected lower cost to patients. Payers ... that meet their pricing expectations in order to ...
Breaking Biology Technology:Regulus Announces Timing for Second Quarter 2014 Financial Results Webcast and Conference Call 2Regulus Announces Timing for Second Quarter 2014 Financial Results Webcast and Conference Call 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 2Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 3Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 4Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 5Regeneron and Sanofi Announce Plan to Use Priority Review Voucher For Alirocumab U.S. FDA Submission 6Grace Launches New REVELERIS® Prep Purification System 2Surveyed U.S. Payers Expect Cost Savings to MCOs and Patients to be the Strongest Drivers of Biosimilar Uptake 2Surveyed U.S. Payers Expect Cost Savings to MCOs and Patients to be the Strongest Drivers of Biosimilar Uptake 3
... computer-based method of analyzing cellular activity has correctly predicted ... in BioMed Central,s open access journal Molecular Cancer ... integrated machinery of the cell and predicts those components ... Skolnick, in collaboration with John McDonald, led a team ...
... La.Evaluations of the first-ever prototype positron emission tomography ... that the scanner could advance the quality and ... at SNM,s 55th Annual Meeting. The prototype scanner ... epilepsy and nasopharyngeal cancer. Eventually, the technology could ...
... physicist Ranjit Pati and his team have developed a ... Grail, the single molecular switch. , If born out ... could revolutionize computing technology. , Moore,s Law predicts that ... on an integrated circuit will double about every two ...
Cached Biology Technology:First semiconductor-based PET scanner demonstrates potential to aid in early diagnosis of disease 2Michigan Tech scientist models molecular switch 2
(Date:7/30/2014)... the Red Queen in Lewis Carroll,s Through the ... and National University of Singapore improved a 35-year-old ... over decades to millions of years. , The ... competition, incorporates the "Red Queen Effect," an evolutionary ... 1970s, which suggests that organisms must constantly increase ...
(Date:7/30/2014)... her eggs until they hatched 4.5 years later, according ... open-access journal PLOS ONE by Bruce Robison ... Octopuses typically have a single reproductive period during their ... their fertilized eggs until they hatch. Shallow-water octopuses typically ... but little is known about the brooding of deep-sea ...
(Date:7/30/2014)... The American Chemical Society (ACS) announced today that David ... ACS Biomaterials Science & Engineering as editor-in-chief. ... 2015, the new journal will feature high-quality research in ... engineered or naturally derived materials that interact with living ... as it reflects the tremendous growth in the field ...
Breaking Biology News(10 mins):Classic Lewis Carroll character inspires new ecological model 2Classic Lewis Carroll character inspires new ecological model 3Deep-sea octopus has longest-known egg-brooding period 2ACS Biomaterials Science & Engineering: Brand-new journal launches in 2015, names editor 2
... yet of the heart of the translocon, a channel ... cell membrane. The process of transporting proteins across or ... every cell. , Howard Hughes Medical Institute investigator Joachim ... their detailed study of the translocon's core, called the ...
... sense light governs everything from seed germination, photosynthesis and ... for the first time, scientists have obtained a detailed ... a protein found in many species across life's plant, ... of the protein known as phytochrome, scientists can now ...
... , Chinese men are selectively switching from traditional ... dysfunction, but sticking with tradition for ailments such ... research published in Environmental Conservation. , The finding ... researchers at the advent of Viagra's commercial release ...
Cached Biology News:Zooming in on the protein-conducting channel 2Zooming in on the protein-conducting channel 3Scientists map one of biology's critical light-sensing structures 2Scientists map one of biology's critical light-sensing structures 3Viagra's hidden help for wildlife 2
... software, PC, is used to perform ... obtained from the Experion automated electrophoresis ... electropherogram and simulated gel views and ... in a Results table. This software ...
... to PRKAR2 cAMP is a signaling ... functions. cAMP exerts its effects by activating ... the signal through phosphorylation of different target ... a tetramer composed of two regulatory and ...
The large Dodeca stainer shaking rack holds the staining trays in the large Dodeca stainer....
...
Biology Products: