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Baseline Research Indicates High Interest in Centocor-Ortho Biotech's SIMPONI(R)
Date:5/8/2009

> (generic name: golimumab) on April 24, 2009. The first once-monthly subcutaneous anti-TNF-alpha therapy, SIMPONI is approved for the treatment of moderately to severely active rheumatoid arthritis, active psoriatic arthritis, and active ankylosing spondylitis. The product will be available in two dosing delivery forms: the SIMPONI SmartJect autoinjector and a prefilled syringe.

LaunchTrends: SIMPONI is a four wave primary market research study that consists of a quantitative on-line survey and qualitative telephone interviews. In total, 300 Rheumatologists will participate in the research. Following a baseline report, three additional waves will be published capturing launch effectiveness at one month, three months, and six months post launch. The reports are designed to assess trial and use of SIMPONI(R), obstacles to use, typical patient types, product perceptions, promotional efforts/messages, and satisfaction with the product relative to other agents. The full baseline report, which incorporates quantitative and qualitative results, will be published on May 22, 2009.

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