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BASF Set To Commercialize pro-t-action(TM) Eliminating Caries Causing Bacteria From the Mouth
Date:4/1/2009

OrganoBalance GmbH and BASF developed pro-t-action(TM) product based on probiotic microorganisms

Active ingredient easily integrated into consumer products for daily oral care

Full research studies introduced at International Association of Dental Research annual conference in Miami, FL, April 1-4

LUDWIGSHAFEN, Germany and MIAMI, April 1 /PRNewswire/ -- With an eye to help remedy a main cause of tooth decay affecting an estimated 5 billion people world-wide, BASF -- The Chemical Company, in collaboration with OrganoBalance GmbH, are set to commercialize pro-t-action(TM). Based on probiotic microorganisms (scientific name: Lactobacillus), the active ingredient in pro-t-action(TM) binds to and eliminates caries causing bacteria (Streptococcus mutans) from the mouth. The Berlin based OrganoBalance is specialized in microbial strain development and microbiological screening. Together the companies identified a very particular strain of Lactobacillus paracasei and BASF has since developed a proprietary production process enabling the active ingredient to be easily integrated into everyday consumer products like toothpaste, mouthwash, candies, lozenges and chewing gums used for daily oral care.

Caries causing bacteria in the oral cavity, like Streptococcus mutans, initiate the onset of tooth decay converting the sugar from food into acids. These acids ultimately destroy tooth enamel, reducing essential minerals protecting the teeth and thus leading to lesions or cavities. Shown in testing, the active ingredient, L. paracasei, in pro-t-action(TM) has the unique ability to very precisely target the caries causing bacteria and bind exclusively to them, and clumping them. When aggregated and grouped together in this way, the bacteria can be flushed out of the oral cavity by normal swallowing or rinsing. Needing to remain in the oral cav
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