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Awareness of Genzyme's Renvela(R) (Sevelamer Carbonate) is High, Although Uptake of this New Phosphate Binding Agent has Been Slower than Nephrologists and Renal Dietitians Initially Expected

EXTON, Pa., May 23 /PRNewswire/ -- BioTrends Research Group, Inc. released Wave 1 of its LaunchTrends(TM): Renvela report, the second in a multi-phase syndicated market research project tracking the launch of Renvela from baseline awareness through the first six months of product availability. The baseline report was published in December 2007. Wave 1 was fielded in April 2008, one month post Renvela launch, and provides quantitative information from 30 clinical Nephrologists and 30 Renal Dietitians (RDs) in the US, and qualitative information from a subset of 15 respondents in each group.

While virtually all Nephrologists and RDs are aware of Renvela, the next generation Renagel (sevelamer hydrochloride), the vast majority have not yet tried the new phosphate binder. Reimbursement is currently the biggest obstacle to use. Genzyme representatives seem to have increased their contact frequency compared to competitors in their promotion of this new product -- most often focusing on Renvela's similarity to Renagel but with fewer incidences of acidosis and better GI tolerability, according to Nephrologists and RDs. Renvela trials for the most part have been in patients switched from Renagel or naive to binder therapy, although depending on patient types, there are switches from competitive products. Each binder is associated with a variety of attributes and each is associated with unique concerns. Renvela is currently perceived to be the best choice for patients with metabolic acidosis.

Despite slower uptake than MDs and RDs predicted in the baseline research, Renvela share is expected to increase in the next six months among both dialysis and CKD patients.

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BioTrends Research Group, Inc. ( provides syndicated and custom market research to pharmaceutical manufacturers competing in clinically evolving, specialty pharmaceutical markets. For information on BioTrends publications and research capabilities, please contact Jennifer Robinson at (610) 363-3872 or

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SOURCE BioTrends Research Group, Inc.
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