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Avid Bioservices Presents Data From Manufacturing Successes Achieved With Single-Use Bioreactor Systems
Date:2/13/2009

TUSTIN and SAN DIEGO, Calif., Feb. 13 /PRNewswire-FirstCall/ -- Avid Bioservices, Inc. today reported that it presented data from several antibody projects using the company's recently installed Single-Use Bioreactors (S.U.B.) at the Thermo Scientific BioProduction Optimization Workshop held this week in San Diego, California. In response to growing demand for its cGMP bioproduction services, Avid installed a HyClone 1000 L S.U.B. in its manufacturing suite in November 2008, complementing the HyClone 100 L S.U.B. that was already installed in Avid's Process Development unit at its production facilities in Tustin, California.

At the workshop, Avid researchers discussed their early successes using the 100 L S.U.B. and 1000 L S.U.B. systems. Avid senior vice president of bioprocess development and manufacturing Richard Richieri presented data on cell culture performance at both the 100 L and 1000 L scale, demonstrating that the process is scalable and that cell growth and production are very similar in the two systems. Avid's initial analysis of the antibody product also shows excellent comparability between these disposable units and traditional reactors.

"We installed our HyClone S.U.B. systems to help meet the rising demand for our biomanufacturing services," said Mr. Richieri. "Our experience to date with these systems has been very positive, and we welcomed the opportunity to share our insights at this workshop with other industry representatives. Avid's commitment to efficient production has led us to innovate in a number of areas, including installing our two HyClone S.U.B. systems and acquiring a ClonePix automated system for optimal clone selection. These new technologies have been very successful in reducing our processing costs and shortening project timelines."

The Thermo Scientific HyClone S.U.B. consists of a reusable stainless steel outer support container and S.U.B. BioPro
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SOURCE Peregrine Pharmaceuticals, Inc.
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