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Automated Online Sample Preparation Comes to Waters UltraPerformance Liquid Chromatography (UPLC) Platform
Date:11/20/2012

letely automated SPE-UPLC based analyses."

Leading laboratories use Spark Holland automated sample preparation devices to streamline sample preparation and analysis for routine, high throughput applications. Scientists employ online solid phase extraction when removing involatile salts, ion suppressing species and other interferences from samples prior to analysis. This reduces analysis time, reduces errors caused by manual SPE procedures, as well as provides a significant improvement in selectivity and concentrates analytes for better sensitivity. Covance Inc., one of the world's largest drug development services companies, employs automated online SPE and reports that it frequently allows quantification of even very large peptides down to the 10 pg/mL level in human plasma.1

In 2007, Waters and Spark Holland announced the availability of the Waters Oasis® brand sorbent line for a newly-designed Spark Holland 800-series format tray for the Spark Holland® Symbiosis™ and Prospekt-2™ systems. For the new system special UPLC® cartridges are offered as well as novel applications. Spark Holland intends to expand its cartridge product line and applications portfolio continuously to serve clinical, pharmaceutical, food safety, and environmental control laboratories.

About Spark Holland (www.sparkholland.com)

Spark Holland has more than 30 years of history in HPLC and UHPLC instrument innovation, specializing in the field of autosampling and online solid phase extraction and, more recently, online dried blood spot analysis. Today, Spark Holland is a leading OEM supplier of front-end UHPLC and online solid phase extraction instruments, working according to ISO 13485 and, when required, delivering CE-IVD compliant
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SOURCE Waters Corporation
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