Navigation Links
Automated Online Sample Preparation Comes to Waters UltraPerformance Liquid Chromatography (UPLC) Platform

MILFORD, Mass., Nov. 20, 2012 /PRNewswire/ -- Waters Corporation (NYSE: WAT) announced today that its ACQUITY UPLC® System is now available with online solid phase extraction (SPE) technology from Spark Holland BV (Emmen, The Netherlands).  The Waters® ACQUITY UPLC Online SPE Manager is based on a special version of the highly-popular Spark Holland online SPE technology, which Spark Holland is making available to Waters exclusively. The Waters ACQUITY UPLC Online SPE Manager is now available as an integrated Waters UPLC/MS system or as an upgrade to installed ACQUITY UPLC Systems under an agreement with Spark Holland. High-throughput analytical laboratories can now streamline sample preparation and analysis time and generate test results faster than before. The integrated system is sold and supported by Waters worldwide.

(Logo: )

"Combining our UPLC technology with Spark Holland's online SPE technology offers compelling benefits to high-throughput laboratories intent on producing the highest-quality test results, quickly and reproducibly for UPLC/MS analyses," said Ian King, Vice President, Separations Technologies, Waters Division. "Automating the process of sample preparation can help laboratories greatly improve turnaround times, reduce errors and the control costs." 

"Coupling online SPE to UPLC efficiently, while maintaining the unique benefit of disposable SPE cartridges, is a major technological challenge that performs best in a completely integrated fashion," said Rob van der Knaap, President, Spark Holland. "Integration of our online SPE technology with the ACQUITY UPLC System creates a superior platform for completely automated SPE-UPLC based analyses."

Leading laboratories use Spark Holland automated sample preparation devices to streamline sample preparation and analysis for routine, high throughput applications. Scientists employ online solid phase extraction when removing involatile salts, ion suppressing species and other interferences from samples prior to analysis. This reduces analysis time, reduces errors caused by manual SPE procedures, as well as provides a significant improvement in selectivity and concentrates analytes for better sensitivity. Covance Inc., one of the world's largest drug development services companies, employs automated online SPE and reports that it frequently allows quantification of even very large peptides down to the 10 pg/mL level in human plasma.1

In 2007, Waters and Spark Holland announced the availability of the Waters Oasis® brand sorbent line for a newly-designed Spark Holland 800-series format tray for the Spark Holland® Symbiosis™ and Prospekt-2™ systems. For the new system special UPLC® cartridges are offered as well as novel applications. Spark Holland intends to expand its cartridge product line and applications portfolio continuously to serve clinical, pharmaceutical, food safety, and environmental control laboratories.

About Spark Holland (

Spark Holland has more than 30 years of history in HPLC and UHPLC instrument innovation, specializing in the field of autosampling and online solid phase extraction and, more recently, online dried blood spot analysis. Today, Spark Holland is a leading OEM supplier of front-end UHPLC and online solid phase extraction instruments, working according to ISO 13485 and, when required, delivering CE-IVD compliant  modules for use in clinical systems. Spark Holland is a privately held firm with operations based in Emmen, The Netherlands.

About Waters Corporation (

For over 50 years, Waters Corporation has created business advantages for laboratory-dependent organizations by delivering practical and sustainable innovation to enable significant advancements in such areas as healthcare delivery, environmental management, food safety, and water quality worldwide.

Pioneering a connected portfolio of separations science, laboratory information management, mass spectrometry and thermal analysis, Waters technology breakthroughs and laboratory solutions provide an enduring platform for customer success.

With revenue of $1.85 billion in 2011, Waters is driving scientific discovery and operational excellence for customers worldwide.

     1.   Bioanalytical Approaches to Analyzing Peptides and Proteins by LC/LC-          MS, Bioanalysis (2011) 3(12), 1379-1397

Waters, Oasis, UPLC, and ACQUITY UPLC are registered trademarks of Waters Corporation.

Spark Holland, Symbiosis, and Prospekt are trademarks of Spark-Holland BV.

SOURCE Waters Corporation
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. JBT Corporation and Swisslog Enter Into Partnership for Automated Guided Vehicles
2. IMDx Obtains CE-Marking for an Automated Molecular Test for Detection and Differentiation of Herpes Simplex Viruses 1 and 2
3. VisionGate Reports Advances In Its Cell-CT(TM) Automated 3D Cell Analysis Platform At ASC 2012 Scientific Meeting
4. AGSES - Your Key to Online Freedom
5. Introducing a New, Easy Way for Industrial Businesses to Join the Online Conversation
6. Two Top Biological Imaging Centers Offer Powerful Free Online Tool to Researchers, Educators, and Public
7. iBioSeminars and iBioMagazine: Free, Online Biology Seminars and Short Talks by Leading Scientists
8. The ABC Clinical Guide to Herbs Now Available Online
9. Free Disaster Preparedness Online Training Course
10. Online Training for Hospital Value Based Purchasing Now Available
11. AAAS To Host Live Online Discussion On 2013 U.S. Federal R&D Budget
Post Your Comments:
(Date:6/27/2016)... ... June 27, 2016 , ... ... findings on what they believe could be a new and helpful biomarker for ... research. Click here to read it now. , Biomarkers are components ...
(Date:6/27/2016)... ... June 27, 2016 , ... Newly created ... services and solutions to the healthcare market. The company's primary focus is on ... sales and marketing strategies that are necessary to help companies efficiently bring their ...
(Date:6/27/2016)... June 27, 2016  Liquid Biotech ... funding of a Sponsored Research Agreement with The ... cells (CTCs) from cancer patients.  The funding will ... levels correlate with clinical outcomes in cancer patients ... will then be employed to support the design ...
(Date:6/24/2016)... 2016  Regular discussions on a range of subjects including ... two entities said Poloz. Speaking at a lecture ... , he pointed to the country,s inflation target, which is ... "In certain areas there ... common economic goals, why not sit down and address strategy ...
Breaking Biology Technology:
(Date:6/7/2016)... -- Syngrafii Inc. and San Antonio Credit Union (SACU) ... Syngrafii,s patented LongPen™ eSignature "Wet" solution into SACU,s ... in greater convenience for SACU members and operational ... document workflow and compliance requirements. Logo ... Highlights: ...
(Date:6/2/2016)... LONDON , June 2, 2016 ... Systems, Manned Platforms, Unmanned Systems, Physical Infrastructure, Support & ... intelligence provider visiongain offers comprehensive analysis of ... that this market will generate revenues of $17.98 billion ... Systems acquired DVTEL Inc, a leader in software and ...
(Date:5/16/2016)... YORK , May 16, 2016   EyeLock ... solutions, today announced the opening of an IoT Center ... to strengthen and expand the development of embedded iris ... an unprecedented level of convenience and security with unmatched ... authenticate one,s identity aside from DNA. EyeLock,s platform uses ...
Breaking Biology News(10 mins):