Navigation Links
Attagene's Breakthrough Transcription Factor Profiling Technology to be Described in Nature Methods
Date:2/25/2008

RESEARCH TRIANGLE PARK, N.C., Feb. 25 /PRNewswire/ -- Attagene Inc., a biotechnology company that develops innovative tools for signal transduction analysis, announced today that one of the Nature Research Journals highlights their flagmanship technology, the FACTORIAL(TM). In advance online publication on Nature Methods' website, Dr. Sergei Romanov with colleagues describes a novel and remarkably consistent method for simultaneously reporting on the activity of a large panel of transcription factors.

"The human genome has tens of thousands of genes, but only a fraction is expressed in a particular cell type at a given time. Understanding how gene expression is regulated is the Grail of the post-genomic era," says Dr. Sergei Makarov, Attagene's President and CEO, and the senior author. "A major hindrance is the lack of appropriate tools. We have found an entirely different way to characterize the functional status of cellular gene regulatory network."

Signals that modulate gene expression are relayed to genomic DNA by an intricate network of intracellular regulatory pathways. These pathways communicate with DNA by using transcription factors, proteins that bind particular sequences within target genes. An estimated few hundreds of transcription factor families hold the keys to regulation of the entire human genome; by assessing transcription factors activities one can capture the status of gene regulatory network. Therefore, Attagene's research team set to develop technology for assessment of activities of multiple transcription factors.

At the core of the proprietary technology, termed FACTORIAL(TM), is a set of reporter DNA constructs specially designed to evaluate particular transcription factors. When introduced into cell, the reporter constructs produce a spectrum of reporter RNA messages that mirror the activities of the evaluated transcription factors. These reporter messages are quantified by using an unconventional detection appr
'/>"/>

SOURCE Attagene Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
2. NeoMatrix Announces Additional Funding for Breakthrough Breast Cancer Screening Test
3. Kingfisher Healthcare Launches Breakthrough Product in Europe
4. New technique can be breakthrough for early cancer diagnosis
5. Breakthrough research identifies how cells from pigs may cure diabetes
6. Harmonex Introduces CliniCom(TM), a Breakthrough in Psychiatric Intake and Assessment Technology
7. Medical Breakthrough ... Doctor Discovers Penetrating Carrier That Eradicates Fungus
8. H&V Introduces HVision Technology Platform to Accelerate Development of Breakthrough Products
9. Discovery Institute Bioethicist Lauds Breakthrough in Stem Cells Research that Eliminates Need for Human Cloning
10. Stem Cell Breakthrough Could End Human Embryonic Experimentation
11. Panacea Pharmaceuticals Lung Cancer Diagnostic Test, LC Detect(SM), Named One of Time Magazines Ten Biggest Medical Breakthroughs of 2007
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... 22, 2014 The Board of Directors of BD ... declared a quarterly dividend of 54.5 cents per common share ... September 9, 2014. The indicated annual dividend rate is $2.18 ... is a leading medical technology company that partners with customers ... and evolving health needs. Our innovative solutions are focused on ...
(Date:7/22/2014)... --  BioTE Medical , a leading provider of ... today announced the addition of Dr. Neal ... is joining the BioTE Medical Advisory Board as ... was residency trained in Family Medicine and Emergency ... emergency physician still practicing at a large metropolitan ...
(Date:7/22/2014)... The DNA Spectrum Ancestry Map ... of history, migration, and culture. , Throughout his ... history stories stemming from Europe. His father passionately referred ... and 8mm home movies painted an elaborate picture of ... Steve ordered a test from DNA Spectrum to expand ...
(Date:7/22/2014)... Massachusetts e SHENZHEN , ... Co., LTD, (BGI Tech), una filiale di BGI, la ... lancio mondiale di un nuovo servizio di sequenziamento dell,intero ... di Complete Genomics. Complete Genomics, molto ... tecnologie di sequenziamento proprietarie con il 99.999% di precisione ...
Breaking Biology Technology:Dr. Neal Rouzier Joins BioTE Medical 2Dr. Neal Rouzier Joins BioTE Medical 3DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 2DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 3DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 4BGI Tech lancia un servizio di sequenziamento dell'intero esoma umano sulla piattaforma avanzata di Complete Genomics 2
... Conn., Dec. 20 /PRNewswire-,FirstCall/ -- Cell Genesys, Inc. ... an,affiliate of GBP Capital, the majority shareholder in ... companies have entered,into an asset sale agreement relating ... to as lentiviral vectors. Pursuant,to the agreement, Cell ...
... BAX ), will host its quarterly conference call to ... 2008, at 8:30 a.m.,Eastern Time (7:30 a.m. Central Time). ... (international). Please dial into,the call at least ten minutes ... to connect you., This call is being webcast ...
... to Correct the Record and Provide Accurate Information to ... ... Dec. 20 VaxGen,Inc. (Pink Sheets: VXGN), (Logo: http://www.newscom.com/cgi-bin/prnh/19991112/VAXGENLOGO ... Raven biotechnologies announced on,November 12, 2007 that their respective Boards of ...
Cached Biology Technology:Cell Genesys Announces Sale of Lentiviral Gene Delivery Technology for $12 Million 2Cell Genesys Announces Sale of Lentiviral Gene Delivery Technology for $12 Million 3Cell Genesys Announces Sale of Lentiviral Gene Delivery Technology for $12 Million 4Cell Genesys Announces Sale of Lentiviral Gene Delivery Technology for $12 Million 5VaxGen Addresses MPM Claims in Letter to Stockholders 2VaxGen Addresses MPM Claims in Letter to Stockholders 3VaxGen Addresses MPM Claims in Letter to Stockholders 4VaxGen Addresses MPM Claims in Letter to Stockholders 5VaxGen Addresses MPM Claims in Letter to Stockholders 6VaxGen Addresses MPM Claims in Letter to Stockholders 7VaxGen Addresses MPM Claims in Letter to Stockholders 8VaxGen Addresses MPM Claims in Letter to Stockholders 9
(Date:7/21/2014)... BATON ROUGE LSU,s Mark Batzer, Boyd Professor and ... Biological Sciences in the College of Science, contributed to ... , titled "The Common Marmoset Genome Provides Insight into ... , Batzer contributed analysis of "jumping genes," or mobile ... paste" mechanism in the genome. The marmoset is important ...
(Date:7/21/2014)... every movement, researchers have shown for the first time ... farms and pipelines. Those man-made structures probably serve as ... study published in the Cell Press journal Current ... shocked when I first saw the stunning grid pattern ... wind farm in the United Kingdom, says Deborah Russell ...
(Date:7/21/2014)... to conserve water and save on your utility bill? ... published in the current issue of the journal ... The Most Effective Actions U.S. Households Can Take to ... use substantially by simple actions such as installing more ... While the suggestions may be familiar, the researchers are ...
Breaking Biology News(10 mins):LSU's Mark Batzer contributes to Nature Genetics article on marmoset genome 2Seals forage at offshore wind farms 2Researchers provide guide to household water conservation 2Researchers provide guide to household water conservation 3
... look like tiny spheres; when they are malignant, ... investigator of the Prion Biology Laboratory at the ... Trieste, when describing prion proteins. Prions are "misfolded" ... diseases, including spongiform encephalopathies (for example, mad cow ...
... did life forms first begin to get larger and what ... with an international team of scientists examined the earliest communities ... answer this question. The life scientists ... of scales to understand the scientific processes operating in the ...
... endured a high frequency of disturbances from volcanic eruptions, ... in the mid-20th century were set to forests in ... In 2010, another 17,000 acres of Patagonia burned, fueling ... of southern South America may contain high phosphorus levels, ...
Cached Biology News:The origin of the evil conformation 2Scientists reveal why life got big in the Earth's early oceans 2Exploring the roots of the problem: How a South American tree adapts to volcanic soils 2Exploring the roots of the problem: How a South American tree adapts to volcanic soils 3
HSV-2 gD (0191)...
...
...
RayBio Human Angiogenesis Antibody Array 2.1 (8 array membranes) with Accessory, detects 23 angiogenic factors (for lysate) Class: Antibody Array Products Product Group: Antibody Array...
Biology Products: