all lab reports to determine cardiovascular disease
risk in CMR patients with low to moderate LDL levels and the calculation of
apoB in patients with CMR who are on medication. As published in Diabetes
Care, the ADA-ACC consensus document also acknowledges the value of
directly measured LDL levels when triglyceride levels exceed 200, a
frequent occurrence in CMR patients. Extending beyond previous guidelines
to specifically address the issue of cardiometabolic risk, the new
statement advises clinicians to measure and treat apoB to goal: apoB below
80 (mg/dl) for the highest risk patients or apoB below 90 for high risk
patients.
Of note is the fact that the consensus document experts specifically
favor apoB, which is considered internationally as the "best reflection of
atherogenic particle burden" and does not currently recommend the
measurement of nuclear magnetic resonance (NMR) derived LDL-P primarily
because of a dearth of clinical evidence and questions about its validity
among various ethnic groups. The report also acknowledges that more
aggressive control of other lipoprotein parameters may be warranted in
those with high concentrations of Lp(a), a particle that is measured in all
VAP samples.
The VAP (Vertical Auto Profile) Test is the most accurate and
comprehensive cholesterol test available today, reporting 15 separate
components of blood cholesterol as opposed to four in a standard test, and
is the only cholesterol test to identify markers for Metabolic Syndrome, a
precursor for diabetes.
The VAP Test provides physicians with direct measurement of LDL, HDL,
and all clinically relevant subclasses, and includes non-HDL, a highly
accurate determination of apo B, emerging risk factors (such as Lp(a), LDL
pattern, density and size) and precise calculations for LDL components. The
test helps to clearly identify individuals with cardiometabolic risk and is
able to identify far more patients at risk for heart disease than the
standard choles
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SOURCE Atherotech, Inc. Copyright©2008 PR Newswire. All rights reserved | |
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