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At Six Months Post-Launch, Neurologist-Reported Patient Share for Tecfidera Among Relapsing-Remitting Multiple Sclerosis Patients Already Rivals that of Gilenya
Date:12/10/2013

ost common reason for Tecfidera discontinuation, as findings suggest that gastrointestinal events are more disruptive to treatment than flushing. Additionally, prescribers report that significantly more patients discontinued Tecfidera due to cost issues compared with three months ago. Neurologists continue to identify cost and managed care issues among the main obstacles to using Tecfidera more, potentially driven by the significant increase in Tecfidera prescription denials by managed care companies for treatment-naive and switched patients. During qualitative interviews, neurologists, while identifying treatment-naive patients among the most likely candidates for Tecfidera, often reported difficulty getting Tecfidera approved as a first-line agent.

"Even with potential access issues, uptake among current nonprescribers and continued use among prescribers will help drive significant growth in Tecfidera patient share to a forecasted 18 percent over the next six months,"  said BioTrends Research Group Senior Business Insights Analyst Emma Williams, Ph.D. "Together with the slight, yet significant, increase in patient shares for Aubagio and Gilenya, oral DMT share is expected to expand to one-third of the market, stealing share from the platform mainstays including Biogen Idec's Avonex, Bayer HealthCare's Betaseron, Teva's Copaxone, and Pfizer/EMD Serono's Rebif, signaling the evolution of the MS treatment algorithm away from injectable drugs."

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