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Astute Medical, Inc. Advancing Next Generation Acute Kidney Injury Biomarkers
Date:2/6/2013

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Researchers reported on a two-part study that initially evaluated 340 biomarkers and found the combination of TIMP-2 and IGFBP7 to have the highest correlation with risk of AKI. Results from the second part of the study validated the utility of TIMP-2 and IGFBP7 and the improved ability of the two-biomarker combination to predict AKI when compared to existing biomarkers.

"Based upon these results, we believe the NephroCheck® Test will be able to help physicians address one of the most costly, deadly and confounding conditions affecting intensive care hospital patients," said Hibberd. "With increasing constraints on healthcare spending, innovative tools such as the NephroCheck® Test will be essential to ensuring that the right resources get to the right patients at the right time."

AKI has been associated with higher cost of care, especially in the intensive care unit (ICU). A 2008 study of post-cardiac surgery patients published in Nephrology Dialysis Transplantation reported that critically ill patients with no AKI had an ICU cost of $13,836 and 1.4 days of length of stay. In comparison, patients with severe AKI had an ICU cost of up to $49,328 and up to 5.4 days of length of stay.

AKI affects up to seven percent of hospitalized patients. The incidence is much higher among critically ill patients, with up to half developing some degree of AKI during their illness.

About Astute Medical, Inc.
Named by the Wall Street Journal as one of the Top 10 Healthcare Start-Ups of 2012, Astute Medical is dedicated to improving the diagnosis of high-risk medical conditions and diseases through the identification and validation of protein biomarkers that can serve as the basis for novel diagnostic tests. The Company's focus is community- and hospital-acquired acute conditions that require rapid diagnosis and risk assessment. Astute Medical's current areas of interest include abdominal pain, acu
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SOURCE Astute Medical, Inc.
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