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AstraZeneca and Banner Alzheimer's Institute Collaborate to Evaluate New Tool Targeting Alzheimer's Disease
Date:12/19/2007

New Alliance Seeks to Advance Understanding of Disease and Clear Path for

New Treatments

WILMINGTON, Del. and PHOENIX, Dec. 19 /PRNewswire-FirstCall/ -- The Banner Alzheimer's Institute and AstraZeneca (NYSE: AZN) today announced that they will collaborate to help advance understanding of Alzheimer's disease and increase knowledge of potential new avenues for treatment through the use of cutting-edge brain imaging methods.

The new alliance will focus on the evaluation and further development of a radioligand discovered by AstraZeneca. This radioligand is a molecule that binds to amyloid plaque -- protein deposits in the brain that are a hallmark of Alzheimer's disease -- and allows the plaque to be measured in real time using a positron emission tomography (PET) scan.

Scientists at the Banner Alzheimer's Institute and AstraZeneca hope to use this new technology to find clues to how the disease progresses and affects the brain, offering a baseline for future studies. The information could potentially be used to monitor the effectiveness of existing treatments, reveal new therapeutic targets and enhance understanding of novel ways to curtail disease progression.

"We look forward to working with AstraZeneca on the development of this promising research tool for the early detection, tracking and scientific study of Alzheimer's disease in the living human brain," said Dr. Eric Reiman, executive director of the Banner Alzheimer's Institute. "Our goals are to advance the scientific understanding of Alzheimer's disease and evaluate promising disease-slowing and prevention therapies in the most rapid and rigorous way."

Alzheimer's disease is the most common form of dementia and affect
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SOURCE AstraZeneca
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