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Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify
Date:8/21/2014

tendering purchase models used in the public sector in both countries, the use of generic LABA/ICS fixed-dose combinations and biosimilar omalizumab is likely to be promoted.
  • Novel IL-5 inhibitors: Surveyed physicians are optimistic about novel IL-5 inhibitors, such as Cephalon/Teva's Cinquil and GlaxoSmithKline's Bosatria.
  • Comments from Decision Resources Group Director Andreia Ribeiro, Ph.D.:

    • "HTA is rapidly becoming the most powerful driver of market access in Brazil and Mexico. Demonstration of statistically superior clinical benefit (preferably head-to-head) in the target population requested for coverage—a detail commonly overlooked in HTA submissions—and positive cost-benefit to the local healthcare systems will be determinant for formulary inclusion of emerging brands."
    • "Existing asthma drugs have shown good efficacy and safety in general, but asthma patients are mostly polymedicated, raising concerns about compliance and overall treatment costs. New drugs (such as the first once-daily LABA/ICS, GlaxoSmithKline/Theravance's Relvar/Relvare) attempt to respond to at least some of these needs but their uptake will be highly dependent on price in these very cost-sensitive markets."

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