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Assay Designs(TM) Announces Collaboration with Medical University of South Carolina (MUSC)
Date:5/5/2008

ANN ARBOR, Mich., May 5 /PRNewswire/ -- Assay Designs, Inc., a leading provider of immunoassay kits, antibodies, and reagents to the life sciences and translational research markets, announced a collaboration on a joint antibody research project with the Medical University of South Carolina and Dr. Jennifer Isaacs' laboratory. Under the terms of this agreement, Assay Designs will provide anti-Heat shock protein 90 (Hsp90) antibody for both cell-based and animal-based work.

This collaboration agreement will allow Dr. Isaacs to move forward with research investigating the role of Hsp90 in the progression of many cancers. "I am excited about the prospect of utilizing this antibody to target the Hsp90 chaperone and to potentially curtail the metastatic properties of some cancers. Moreover, we now have a new tool to explore the role of cell surface localized Hsp90 protein in cancer progression. Since this antibody is well-tolerated in animals, this approach paves the way for a promising therapeutic strategy, " stated Dr. Isaacs.

"As the leader in heat shock proteins (HSPs) and chaperones, collaborations such as this provide valuable insight for our new product development efforts," stated Dan Calvo, Assay Designs' President and CEO. "Supporting the validation of new and novel test protocols enhances the value and flexibility of our broad HSP product portfolio."

About Assay Designs, Inc.

Based in Ann Arbor, MI, Assay Designs develops, manufactures and markets immunoassay (ELISA) kits, antibodies, and proteins that are used for life sciences research. The company markets these products under the "Assay Designs" and "Stressgen" brand names. Researchers use Assay Designs products to detect and quantify molecules that are important biomarkers of inflammation, heat shock, cell signaling, and oxidative stress.

About Isaacs Lab.

A long-term research goal of the Isaacs Lab is to better understand the role of Hsp90 in tumor progression to ultimately optimize the use and potency of Hsp90 inhibitors in the clinic. In particular, the lab investigates how Hsp90 contributes to angiogenic processes and cell migration, representing two fundamental and universal aspects of cancer progression. Specifically, the tumor-promoting roles of Hsp90 are being assessed in various invasive cancers, such as prostate, renal cell carcinoma (RCC), and the deadly disease glioblastoma (GBM). Clinically relevant orthotopic models of RCC and GBM are being used and newer forms of Hsp90 antagonists are being evaluated. In collaboration with other groups, there is also interest in identifying combination treatments most effective against these cancers.


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SOURCE Assay Designs, Inc.
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