Navigation Links
Array BioPharma Provides Updates On Clinical Data At The 2012 American Society Of Hematology Meeting
Date:12/10/2012

BOULDER, Colo., Dec. 10, 2012 /PRNewswire/ -- Array BioPharma Inc. (NASDAQ: ARRY) today announced positive data for ARRY-520 and ARRY‑614 at the 2012 Annual Meeting of the American Society of Hematology (ASH) in Atlanta, Georgia.  

(Logo:  http://photos.prnewswire.com/prnh/20121029/LA02195LOGO)

New results presented at the meeting for ARRY-520 in addition to those described in the abstracts published by ASH in early November included:

  • Overall survival of 19 months and progression free survival of 3.7 months were observed in multiple myeloma patients taking ARRY-520 alone
  • A clinical benefit rate (≥MR) of 50% was observed in heavily pre-treated (median 10 prior regimens) multiple myeloma patients taking ARRY-520 plus dexamethasone who were selected for low AAG levels 
  • Initial signs of clinical activity were observed in the ongoing ARRY-520+Kyprolis® (carfilzomib) combination trial: 56% clinical benefit rate (≥MR)

In a Phase 2 trial with ARRY-520 in patients with triple-refractory multiple myeloma and a median number of 10 prior treatment regimens, ARRY-520 plus low-dose dexamethasone demonstrated a 22% overall response rate (≥ partial response, or PR), with manageable safety. The most common drug-related adverse events include myelosuppression, fatigue and mucosal inflammation. This response rate is comparable to the response rates reported in pomalidomide and Kyprolis studies, which included patients with only half the number of median prior treatment regimens.  

As presented at ASH, researchers found that AAG (acute phase protein alpha-1-acidic glycoprotein) may be a biomarker enabling better patient selection for response to ARRY-520.  A related abstract asse
'/>"/>

SOURCE Array Biopharma
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Array BioPharma Announces Exercise And Closing Of Underwriters Over-Allotment Option
2. John A. Orwin Joins Array BioPharma Board Of Directors
3. Array BioPharma To Present Clinical Data At The 2012 ASH Meeting On ARRY-520, A KSP Inhibitor, And ARRY-614, A Dual p38/Tie2 Inhibitor
4. Array BioPharma to Hold Conference Call on Monday, November 5, 2012 to Discuss Submitted ASH Abstracts
5. Solar nanowire array may increase percentage of suns frequencies available for energy conversion
6. RayBiotech, Inc. and the University of Oslo Enter into Antibody Array Services Collaboration
7. Phalanx Biotech Group Announces CytoOneArray®, a Targeted Chromosomal Microarray
8. Self-assembling nanorods: Berkeley Lab researchers obtain 1-, 2- and 3-D nanorod arrays and networks
9. Maine Manufacturing, LLC Announces Global Distribution of FAST® Protein Array Products
10. Quanterix Develops Microfluidic Consumable That Will Enable Next Generation Molecular Diagnostic Systems based on Single Molecule Array Technology
11. TransCelerate BioPharma Inc. Appoints Dalvir Gill as Chief Executive Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/29/2015)... BioNano Genomics, Inc., the leader in genome ... today that a collaboration led by the Icahn School ... of the first comprehensive analysis of a diploid human ... sequencing and genome mapping. This study, published today in ... the contiguous diploid human genome assembly obtained without using ...
(Date:6/29/2015)...  Neuralstem, Inc. (NYSE MKT: CUR), a biopharmaceutical company ... and cell therapy treatments for central nervous system diseases, ... on the NASDAQ Capital Market under the symbol "CUR." ... the NYSE MKT until the market close on July ... expected to commence on July 13, 2015. ...
(Date:6/29/2015)... , June 29, 2015   Veracyte, Inc . ... the field of molecular cytology, today announced that it ... prestigious Top Workplaces list for the second year in ... based solely on an annual survey of Bay Area-company ... that the degree to which Veracyte values our employees ...
(Date:6/26/2015)... 2015  SeraCare Life Sciences, a leading partner ... that it has signed a Cooperative Research and ... (NCI), part of the National Institutes of Health, ... cancer assays.  The CRADA will investigate the development ... DNA biosynthetics spiked into a genomic DNA background ...
Breaking Biology Technology:BioNano Mapping Technology Achieves Most Contiguous Clone-free Human Genome Assembly to Date 2BioNano Mapping Technology Achieves Most Contiguous Clone-free Human Genome Assembly to Date 3Neuralstem, Inc. Announces Approval for Listing on the NASDAQ Capital Market 2Neuralstem, Inc. Announces Approval for Listing on the NASDAQ Capital Market 3Veracyte Named a 2015 "Top Workplace" in the San Francisco Bay Area 2Veracyte Named a 2015 "Top Workplace" in the San Francisco Bay Area 3SeraCare Life Sciences Signs CRADA with NCI to Advance Cancer Diagnostics 2SeraCare Life Sciences Signs CRADA with NCI to Advance Cancer Diagnostics 3
... to design computer chips and electronic circuitry for extreme ... electrical engineers at Vanderbilt University has developed all the ... thin films of nanodiamond. They have created diamond versions ... a key element in computers., "Diamond-based devices have the ...
... Mass., Aug. 4, 2011 Interleukin Genetics, Inc. ... call and Webcast on Friday, August 12 at 9:30 a.m. ... To access the live call, dial 877-324-1976 (domestic) or 631-291-4550 ... will be available on the Investors section of Interleukin Genetics, ...
... N.J., Aug. 4, 2011 Palatin Technologies, Inc. (NYSE ... of a Phase 1 clinical trial of AZD2820, a ... a single-agent therapy for the treatment of obesity. AZD2820 ... collaborative research program with Palatin Technologies. Obesity ...
Cached Biology Technology:Designing diamond circuits for extreme environments 2Designing diamond circuits for extreme environments 3Interleukin Genetics, Inc. Announces Conference Call to Discuss Second Quarter 2011 Results 2Palatin Announces Commencement of a Phase 1 Trial for Obesity Compound in Collaboration with AstraZeneca 2Palatin Announces Commencement of a Phase 1 Trial for Obesity Compound in Collaboration with AstraZeneca 3
(Date:6/23/2015)... June 22, 2015 ... addition of the "Body-Worn Temperature Sensors Market ... and Forecast 2014 - 2020" report to ... analysis of the global body-worn temperature sensors market. ... segmented on the basis of types, care setting, ...
(Date:6/18/2015)... This report analyzes the worldwide markets for ... Segments, which includes Immunoassay Analyzers and Reagents: Enzyme Immunoassay ... Systems, and Nephelometric Immunoassay Systems. The report provides separate ... , Japan , Europe ... Latin America , and Rest of World. Annual ...
(Date:6/17/2015)... Germany , June 17, 2015 ... Standard: QIA) today launched new Investigator ® STR assay ... the United States . The new genetic ... key genomic markers (short tandem repeats or STRs) for DNA ... evaluate the quality of DNA in each sample, a novel ...
Breaking Biology News(10 mins):Body-Worn Temperature Sensors Market - Global Industry Analysis 2Global Immunoassay Systems Market 2Global Immunoassay Systems Market 3Global Immunoassay Systems Market 4Global Immunoassay Systems Market 5Global Immunoassay Systems Market 6Global Immunoassay Systems Market 7Global Immunoassay Systems Market 8Global Immunoassay Systems Market 9Global Immunoassay Systems Market 10Global Immunoassay Systems Market 11Global Immunoassay Systems Market 12Global Immunoassay Systems Market 13Global Immunoassay Systems Market 14Global Immunoassay Systems Market 15Global Immunoassay Systems Market 16Global Immunoassay Systems Market 17Global Immunoassay Systems Market 18Global Immunoassay Systems Market 19Global Immunoassay Systems Market 20Global Immunoassay Systems Market 21Global Immunoassay Systems Market 22Global Immunoassay Systems Market 23Global Immunoassay Systems Market 24Global Immunoassay Systems Market 25Global Immunoassay Systems Market 26Global Immunoassay Systems Market 27Global Immunoassay Systems Market 28Global Immunoassay Systems Market 29QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 2QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 3QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 4QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 5
... 2011 The collaboration of two leading cell image ... facility for archiving, sharing, and analyzing microscope images in ... (ASCB) and the National Center for Microscopy and Imaging ... (UCSD), have joined forces to provide a unified interface. ...
... University is subjecting chunks of rock to hellish conditions in ... change. By exposing a handful of rocks ... new data about the large-scale underground storage of carbon dioxide, ... "About 60 percent of the world,s carbon ...
... a deadly batch of spinach killed three people and sickened ... line have argued over how best to protect consumers and ... Now, a major, national initiative, led by University of Maryland ... more trustworthy salad fixings. It promises to be one of ...
Cached Biology News:2 top biological imaging centers offer powerful free online tool to researchers and public 2AGU meeting: Stanford scientists subject rocks to hellish conditions to combat global warming 2AGU meeting: Stanford scientists subject rocks to hellish conditions to combat global warming 3AGU meeting: Stanford scientists subject rocks to hellish conditions to combat global warming 4Salads you can trust -- safe farm practices get major test 2Salads you can trust -- safe farm practices get major test 3Salads you can trust -- safe farm practices get major test 4
Recombinant Ovine (Sheep) Prolactin, Ultra Pure...
Human SCP3 Affinity Purified Polyclonal Ab Keywords: Spermatogenesis, meiosis Protein Family: Cell Cycle...
Homo sapiens alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5), mRNA....
Human Rad1 MAb (Clone 33)...
Biology Products: