Arpida Presents Preclinical Data on AR-247... ( REINACH and BASEL Switzerland Sep...)

Arpida Presents Preclinical Data on AR-2474 at ICAAC

Date:9/21/2007

REINACH and BASEL, Switzerland, September 21 /PRNewswire-FirstCall/ -- Arpida Ltd (SWX: ARPN) presented several preclinical studies on its novel topical antibiotic AR-2474 at the 47th annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Chicago. ICAAC is a major scientific conference where thousands of scientists and clinicians from all over the world gather to discuss the latest developments in the field of infectious diseases.

AR-2474 is a novel synthetic antibacterial currently under development for topical indications including treatment of infections and prevention of transmission of the "superbug" MRSA. AR-2474 is a diphenyl urea with unique properties.

F1-2100: The topical activity and potency of AR-2474 was compared with the gold standard mupirocin (Bactroban(R)) in two preclinical models of MRSA infection of the skin and of nasal decolonisation. In both models, a preliminary topical formulation of AR-2474 was demonstrated to be as efficacious as mupirocin.

F1-2094, F1-2095, F1-2096, F1-2097, F1-2100A: The in vitro microbiological activity of AR-2474 and of other compounds of the class was assessed in-house and by leading laboratories against large panels of clinical isolates. AR-2474 showed potent activity against methicillin susceptible and resistant staphylococci including nosocomial and community S. aureus isolates. Importantly, AR-2474 exhibits no cross-resistance with other classes of currently used topical treatments. The compound also exhibited potent activity against Group A and B streptococci, enterococci, pneumococci and other important pathogens responsible for causing infections of the skin, eye and mouth.

F1-2099: AR-2474 demonstrated little or no propensity for resistance development. No resistant mutants to AR-2474 could be selected using different methodologies.

F1-2098: The data showed that AR-2474 is bactericidal, exhibits a post antibiotic effect and shows no antagonism wi
'/>"/>

SOURCE Arpida Ltd.
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3
Related biology technology :

1. NimbleGen presents new tech for comparing microbe DNA
2. Wisconsin Technology Network presents symposium on saving lives by the use of Information Technology
3. Thieme Presents Unique Technology Angle at Gov.s Conference

Post Your Comments:

(Date:5/21/2013)... May 22, 2013 First patients ... of glycopyrronium bromide designed using Prosonix, particle engineering platform ... a portfolio of inhaled Respiratory Medicines by Design ... PSX1002 that will assess its effect on lung function ... patients with moderate to severe chronic obstructive pulmonary disease ...

(Date:5/21/2013)... Through science fairs, workshops, kits for building optical ... organizations will continue their work to increase awareness about ... daily life with the aid of SPIE Education ... countries, are the first of two groups of recipients ... international society for optics and photonics , in 2013. ...

(Date:5/21/2013)... Savoury Systems International (SSI), a leader in ... Southeastern USA Sales Broker. Braddy’s new role will allow ... Southeast. , In 2004 Braddy founded Southeastern ... food processors and industrial manufacturers. Braddy has worked ... and has over 25 years of sales management experience. ...

(Date:5/21/2013)... 21, 2013 As the R&D ... push within the industry to deliver better products, ... and pharma companies often means turning big ideas ... developed in collaboration with Sensidose AB and Recipharm, ... bring products to market sooner. The partnership resulted ...

Breaking Biology Technology:Prosonix Initiates Phase 2 Clinical Study with PSX1002 in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) 2 Prosonix Initiates Phase 2 Clinical Study with PSX1002 in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) 3 Prosonix Initiates Phase 2 Clinical Study with PSX1002 in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) 4 Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants 2 Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants 3 The Development of an Innovative Microtablet Dosage Form, a Success Story: Live Webinar Hosted by Xtalks 2

[0] Prosonix Initiates Phase 2 Clinical Study with PSX1002 in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)[0] Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants [0] Savoury Systems International Bolsters Sales Force in Southeast U.S.[0] The Development of an Innovative Microtablet Dosage Form, a Success Story: Live Webinar Hosted by Xtalks

... 7, 2011 Reportlinker.com ... report is available in its catalogue: ... Shares, Strategies, and Forecasts, Worldwide, 2011 ... http://www.reportlinker.com/p0569001/Tele-Health-Monitoring-Market-Shares-Strategies-and-Forecasts-Worldwide-2011-to-2017.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=e-Healthcare WinterGreen Research ...

... is available in German . ... supplements. However, the production of this "functional food" has ... enough to survive conventional production processes. Researchers from Technische ... that allows the use of thus far unutilized probiotics. ...

... are among the oldest known life-forms, but they are ... that these single-celled microorganisms were designated as a domain ... eukaryotes. Robert Gunsalus, a UCLA professor ... in Archaea because of their ability to ...

Tele-Health Monitoring: Market Shares, Strategies, and Forecasts, Worldwide, 2011 to 2017 TUM researchers develop environmentally friendly process to improve storage stability of probiotics Old life capable of revealing new tricks after all

(Date:5/21/2013)... Researchers at the University of Illinois at Chicago College of ... and stores fat -- its main energy source -- and ... disease, under a new $2 million, 4-year grant from the ... heart changes how it uses fuel for energy. These changes ... disease and are different in men and women, says E. ...

(Date:5/21/2013)... charted the path of insulin action in cells in ... blueprint for understanding what goes wrong in diabetes. ... Professor David James from Sydney,s Garvan Institute of Medical ... of the prestigious journal Cell Metabolism . , ... very important role in the body because it helps ...

(Date:5/20/2013)... is known about the effect of physical education (PE) ... University finds that increasing the amount of time that ... of obesity. , The study represents some of the ... youth obesity, and is forthcoming in the Journal ... of the study can be viewed at: http://www.sciencedirect.com/science/article/pii/S0167629613000556 ...

Breaking Biology News(10 mins):Do men's and women's hearts burn fuel differently? 2 Insight into the dazzling impact of insulin in cells 2 Insight into the dazzling impact of insulin in cells 3 Gym class reduces probability of obesity, study finds for first time 2

[0] Do men's and women's hearts burn fuel differently?[0] Insight into the dazzling impact of insulin in cells [0] Gym class reduces probability of obesity, study finds for first time

... A study published in this week,s online issue of ... sensitive method for detecting methylation-associated cancers. ... of methyl groups has been established as a common ... levels of DNA methylation, which effectively disrupt the genes ...

... research shows that air pollution in eastern China has reduced ... and decreased by 23 percent the number of days of ... results suggest that bad air quality might be affecting the ... health and environmental problems. The study links for the ...

... Dresden research team used laser tweezers to measure the ... track. The team found that also within our ... are restrained in its operationusually by far not as ... experimental measurements of protein friction could help researchers to ...

Cached Biology News:Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer 2 Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer 3 The sky is not falling: Pollution in eastern China cuts light, useful rainfall 2 The sky is not falling: Pollution in eastern China cuts light, useful rainfall 3 The sky is not falling: Pollution in eastern China cuts light, useful rainfall 4 Bionanomachines -- proteins as resistance fighters 2

Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer The sky is not falling: Pollution in eastern China cuts light, useful rainfall Bionanomachines -- proteins as resistance fighters

Request Info...

Applications: (+) Immunocytochemistry and immunohistochemistry...

RABBIT ANTI WARFARIN...

Request Info...

Biology Products:

Rat IFN-gamma ELISpot Development Kit from R&D Systems Normal Goat Serum from Cayman Chemical Rabbit Anti-WARFARIN Polyclonal Antibody, Unconjugated from AbD Serotec MagCellect Rat CD4+ T Cell Isolation Kit from R&D Systems