Navigation Links
Arpida Interim Results for six Months to 30 June 2007
Date:8/28/2007

ntracted in the community setting.

In August 2006, the UK Medicines and Healthcare products Regulatory Authority granted authorisation to start first-in-man studies with AR-709. Results were published on 29 March 2007. These showed that AR-709 achieves high concentrations in the key compartments of the lungs where pathogens can reside and replicate. Moreover, the results of the studies showed that AR-709 exhibited a large volume of distribution and a long half life in man. Three possible routes of administration are under investigation: intravenous, oral and targeted delivery. The latter could have the added benefit of avoiding unnecessary systemic exposure.

Additional studies are ongoing in order to initiate Phase I studies in humans.

AR-2474

AR-2474 originates from Arpidas own drug discovery efforts. It is an antibiotic with a novel mechanism of action that has demonstrated, both in vitro and in vivo, to be highly effective in eradicating multi-drug resistant bacteria known to cause topical infections. AR-2474 is being developed as a topical therapy for different applications, including infections of the skin and eye as well as nasal carriage of MRSA.

In March, results from preclinical studies were published, showing AR-2474 to be at least as efficacious as the gold standard mupirocin (Batroban ) in two distinct preclinical models of MRSA infection of the skin and MRSA nasal carriage.

Additional preclinical studies are currently ongoing.

Early-stage research programmes

Arpida has a number of programmes at earlier research stages. Efforts are focussed on a number of selected targets. Crystallisation and co-crystallisation of these target proteins and inhibitory molecules could open up new avenues for rational drug design.

Organisation

In February 2007 Arpida announced an important focusing of the research organisation, concentrating operations in the headquarters in Reinach, Switzerland. This strategic re-
'/>"/>

SOURCE Arpida
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related biology technology :

1. Effects of Thermal Cycler Well-To-Well Temperature Uniformity on PCR Results
2. HotMasterAn innovative Hot Start/Cold Stop technology for better PCR* results
3. Achieving Reliable Protein Quantitation Results Using ICAT Reagents, MALDITOF Mass Spectrometry, and Advanced Data Interpretation Tool
4. How Best Buy said bye to burnout, hello to results
5. Economic survey reveals better 2006 results
6. Third Wave Reports Third-Quarter Financial Results
7. Tech Digest: Merge eMed product updates; Renaissance Learning 3rd qtr results
8. Midwest small-cap life sciences turn in mixed third-quarter results
9. To boost advertising results, consider improving your web site
10. RedPrairie Reports Strong Results
11. 2003 Biotech Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... Dec. 23, 2014 Vermillion, Inc. (Nasdaq: ... gynecologic disease, announced today that investors including Oracle ... Fund LLC and several Vermillion directors have agreed ... of Vermillion,s common stock and warrants to purchase ... private placement.  Under the terms ...
(Date:12/22/2014)... (PRWEB) December 22, 2014 The ... global leader of technical training across the life sciences ... Data Management (SCDM) to provide the organization's members ... programs —providing access to the more than 350 sessions ... members with 10% off when registering for a ...
(Date:12/22/2014)... Calif. , Dec. 22, 2014  ( www.competitivehealth.com ... CoPatient, an online medical bill review and advocacy service, ... in the FREE WellCard Savings discount health services marketplace. ... bill that was more than they expected to pay. ... reduce health care costs, WellCard Savings is pleased to ...
(Date:12/19/2014)... Charm Sciences is pleased to announce that its ... M1 in raw commingled milk is the first lateral ... peer reviewed report of the validation by Technology and ... Fisheries Research (ILVO-T&V) has been published by the Taylor ... toxic aflatoxin and a known carcinogen, can be passed ...
Breaking Biology Technology:Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5CfPIE Announces Partnership with the Society for Clinical Data Management 2CfPIE Announces Partnership with the Society for Clinical Data Management 3WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2Charm Sciences Achieves Independent Validation of First 15 Minute Quantitative Screening Method for Aflatoxin M1 2
... William Heiser, Ph.D., Research ... Hercules, CA 94547, , ... We have found that the most ... distance and,microparticle size. Changing most other parameters, within a,broad range, ...
... A. Kimberley McAllister, Nina Tang, Lawrence C. Katz, and Donald ... Department of Neurobiology, Box 3209, Duke University Medical Center, , ... , Introduction ... cells and tissues of interest , remains a rate-limiting ...
... Katja Kapp, Werner Kunz, and Christoph G Grevelding,Institute for Genetics, Center of ... , Introduction ... parasitic helminths that cause bilharzia (schistosomiasis) , ... al.1997). , One focus of ...
Cached Biology Technology:Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 2Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 3Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 4Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 5Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 6Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 7Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 8Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 9Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 10Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 11Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 12Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 13Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 14Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 15Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 16Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System 17Biolistic Transfection of Organotypic Brain Slices 2Biolistic Transfection of Organotypic Brain Slices 3Biolistic Transfection of Organotypic Brain Slices 4Biolistic Transfection of Organotypic Brain Slices 5Biolistic Transfection of Organotypic Brain Slices 6Biolistic Transfection of Organotypic Brain Slices 7Biolistic Transfection of Organotypic Brain Slices 8Biolistic Transfection of Organotypic Brain Slices 9Biolistic Transfection of Organotypic Brain Slices 10Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A 2Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A 3Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A 4Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A 5Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A 6Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A 7Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A 8Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A 9
(Date:12/10/2014)... -- You,ve been here before: you desperately need to sign ... site key or the answer to your secret question. What,s ... Today, Hoyos Labs , a digital infrastructure ... put an end to the frustration that comes with usernames, ... leverages a user,s smartphone to acquire his or her biometrics ...
(Date:12/10/2014)... Research and Markets ( http://www.researchandmarkets.com/research/xclcvw/biometrics_market ... "Biometrics Market in Japan 2014-2018" report to ... The integration of biometrics and ... and upgradation of the driver,s license is one ... Besides the aforementioned projects, biometrics is being used ...
(Date:12/4/2014)... Fla. , Dec. 3, 2014  Crossmatch™, ... today announced that its DigitalPersona ® Pro ... readers have been deployed throughout First Bank branch ... South Carolina and Virginia. First ... Southern Pines, North Carolina , ...
Breaking Biology News(10 mins):The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3
... launched a collaborative project to develop and evaluate new ... AvecNet is a five year, 12 million project ... the European Union,s Seventh Framework programme. Because malaria ... to combating the disease. Wide scale use of ...
... and the United Kingdom have been awarded funding ... process of biological photosynthesis. The U.S. National Science ... Sciences Research Council (BBSRC) collaborated in issuing these ... to use sunlight and carbon dioxide to produce ...
... a resident in Medical Genetics in the Department of ... Medical Center, in Stanford Calif., was honored as the ... Foundation Clinical Genetics Fellowship in Biochemical Genetics at the ... Canada. The objective of the Genzyme/ACMG Foundation Award ...
Cached Biology News:€12 million ($16.9 million) project to develop new tools for malaria control 2NSF announces new awards that will investigate more efficient ways to harvest sunlight 2NSF announces new awards that will investigate more efficient ways to harvest sunlight 3NSF announces new awards that will investigate more efficient ways to harvest sunlight 4
KAI 1 (G-2)...
Anti-Mouse Valpha 2 TCR, Purified (Clone B20.1) (rat IgG2a)...
Anti-OSMR Monoclonal Antibody Research Focus: cytokine/growth factor Storage: 4C Shipping Temperature: 4C...
... Yeast Cells are designed for use with ... cerevisiae strain MaV203 contains deletions in the ... with GAL4-based two-hybrid systems. The strain also ... of ProQuest bait and prey vectors. MaV203 ...
Biology Products: