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TORONTO, Sept. 7 /PRNewswire-FirstCall/ - ARIUS Research Inc., (TSX: ARI), a biotechnology company discovering and developing the next wave of antibody therapeutics, today announced that it will deliver poster presentations at two scientific conferences reporting preclinical data for two of its anti-cancer antibody drug candidates.
At the 2007 Breast Cancer Symposium in San Francisco on September 7-8, Arius will report recent results of its antibody candidate that targets CD44, an antigen implicated as a cancer stem cell marker. The poster outlines recent results for this antibody which demonstrate that it is a potent therapeutic in breast cancer models both in vivo and in vitro. The poster also highlights the prevalence of the epitope targeted by Arius' antibody in breast cancer patients.
The poster presentation is entitled "Development of a potent therapeutic monoclonal antibody targeting CD44 in breast cancer" and will be presented at General Poster Session D, 11:45-12:45 pm on Saturday, September 8th at the San Francisco Marriott.
At the XIth European Meeting on Complement in Human Disease held in Cardiff, Wales on September 8-11, Arius will report results demonstrating that its monoclonal antibody targeting CD59, a cell surface molecule involved in regulating cell lysis mediated by the complement system, is a potent therapeutic in various in vivo cancer models. Arius has demonstrated that its antibody is highly potent at low doses and its efficacy in certain models compares favorably to Taxotere.
The poster presentation is entitled "AR36A36.11.1, a monoclonal antibody targeting CD59, enhances complement activity and exhibits potent in vivo efficacy in multiple human cancer models" and will be presented at Poster Session 1: Inflammatory diseases, therapeutics and diagnostics, 4:00-6:00 pm on Sunday, September 9th at Cardiff City Hall, Cathay's Park.
About ARIUS
ARIUS is a biotechnology company discovering and developing
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