Navigation Links
Argonne Researchers Develop Method that Aims to Stabilize Antibodies
Date:9/3/2009

Technique could lead to improved detection, diagnostics capabilities

Argonne, IL (PRWEB) September 3, 2009 -- Researchers at the U.S. Department of Energy's Argonne National Laboratory have developed a systematic method to improve the stability of antibodies. The technique could lead to better biosensors, disease therapeutics and diagnostic reagents and non-laboratory applications, including environmental remediation.

Antibodies are proteins produced by humans and animals to defend against infections; they are also used to diagnose and treat some diseases and detect toxins and pathogens. "The primary issues with antibodies is that they are fragile and short-lived outside of cooler temperature-controlled environments, making their usefulness usually limited to laboratory applications," said Argonne senior biophysicist Fred Stevens, the project's principle investigator.

Specifically, "stabilized antibodies, with full functionality, could be used in diagnostic and detection kits that can survive in less than optimal environments and be stockpiled for years at a time," Stevens said. "They could be used to combat diseases like cancer. They can also be used as the basis for biosensors that can continuously detect for pathogens like botulinum, ricin and anthrax in places such as airports and subway stations - locations where it is not currently possible to provide ongoing detection of pathogens because antibodies cannot tolerate the environmental conditions."


Argonne has provided funding toward Stevens' research. Earlier research funded by the National Institutes of Health showed that it was possible to stabilize antibodies after a team led by Stevens unexpectedly discovered that natural antibodies contain stabilizing amino acid replacements.

Antibodies are made up of four polypeptides -- two light chains and two heavy chains
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Page: 1 2 3 4

Related biology technology :

1. Argonne researchers win 2 R&D 100 Awards
2. Argonnes Lithium-Ion Battery Technology to be Commercialized by Japans Toda Kogyo
3. Argonne researcher studies what makes quantum dots blink
4. Argonne scientist to give the plenary talk at Royal Society of Chemistry meeting on nanoalloys
5. Researchers design new graphene-based, nano-material with magnetic properties
6. ChemBridge Corporation and Collaborative Drug Discovery Announce Strategic Collaboration to Provide Diverse Chemical Libraries Together With Researchers Own Private Data
7. Dartmouth researchers propose new way to reproduce a black hole
8. Nucleix Researchers Discover DNA Evidence May Easily be Falsified: Company Develops New Detection Technology for Preventing Biological Identity Theft
9. K-States Biosecurity Research Institute Gives Researchers the Tools Needed to Study Diseases That Cost Pig Producers Hundreds of Millions of Dollars Each Year
10. Sigma-Aldrich Acquires ChemNavigator, Inc., to Provide Researchers With Industry-Leading Chemical Compound Selection and Procurement Services
11. UCSF researchers help crack parasite genome, identify drug leads
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Argonne Researchers Develop Method that Aims to Stabilize Antibodies 
(Date:1/14/2014)... (PRWEB) January 14, 2014 iLab Solutions, the ... as the new Director of Product Strategy. In this role, ... as iLab sub-teams to guide in the development of iLab ... provides the maximum possible benefit to the scientific community by ...
(Date:1/14/2014)... MD (PRWEB) January 14, 2014 ... to developing innovative information technology solutions for patients, ... health care stakeholders, announced today the signing of ... US Food and Drug Administration (FDA). This ...
(Date:1/14/2014)... Orange, CA (PRWEB) January 14, 2014 Kerr ... a 10-minute video and additional how-to information about dual arch ... Great Restorations with Dual Arch Impressions,” the blog entry serves ... the technique and houses a step-by-step demonstration by Dr. David ...
(Date:1/14/2014)... BioMedomics, Inc. , a Point of Care ... novel disease specific POC tests, announced today that it has ... of $690,000. The investment is from private investors and is ... of private investors has significant successful experience in early investments ...
Breaking Biology Technology:iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2BioMedomics, Inc. Closes $690K Round of Financing 2
... AMSTERDAM, August 17 SynCo ... Inc. today,announced a strategic partnership to produce Versartis, lead ... to treat type 2 diabetes,Under the agreement, SynCo will ... optimize the manufacturing process to,increase yields for the forthcoming ...
... /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc.,(Nasdaq: CHBT ) ("China-Biotics", "the ... marketing and,distribution of probiotics products, today announced its financial results ... 30, 2009. , , First Quarter 2010 ... to $15.4 million, -- Gross profit rose ...
... water for granted, that ordinary tap water could become deadly ... School of Physics and Astronomy. To combat the threat ... the physicist has developed a new system to monitor the ... time. Modifying special fibers developed in his Tel ...
Cached Biology Technology:SynCo Bio Partners to Manufacture Versartis Novel Drug for Type 2 Diabetes 2China-Biotics, Inc. Reports First Quarter Fiscal 2010 Financial Results 2China-Biotics, Inc. Reports First Quarter Fiscal 2010 Financial Results 3China-Biotics, Inc. Reports First Quarter Fiscal 2010 Financial Results 4China-Biotics, Inc. Reports First Quarter Fiscal 2010 Financial Results 5China-Biotics, Inc. Reports First Quarter Fiscal 2010 Financial Results 6China-Biotics, Inc. Reports First Quarter Fiscal 2010 Financial Results 7China-Biotics, Inc. Reports First Quarter Fiscal 2010 Financial Results 8China-Biotics, Inc. Reports First Quarter Fiscal 2010 Financial Results 9China-Biotics, Inc. Reports First Quarter Fiscal 2010 Financial Results 10China-Biotics, Inc. Reports First Quarter Fiscal 2010 Financial Results 11Monitoring water through a snake's eyes 2Monitoring water through a snake's eyes 3
(Date:7/9/2014)... of studies suggest that children delivered by Caesarean section have ... But it is still unknown why this is the case ... the Faculty of Health and Medical Sciences therefore decided to ... immune system in a study of newborn mouse pups. ... Caesarean section had developed a lower number of cells that ...
(Date:7/9/2014)... switch out one gene for another in a line ... fiction to reality within this decade. As with any ... of fixing disease-causing genes in humans, for example--as well ... put one of those concerns to rest: using gene-editing ... of mutations in the cells. The new results were ...
(Date:7/9/2014)... Ind. - Regulated deer hunts in Indiana state parks ... decades of damage caused by overabundant populations of white-tailed ... led by Michael Jenkins, associate professor of forest ecology, ... policy of organizing hunts in state parks has successfully ... wildflowers rendered scarce by browsing deer. , Jenkins ...
Breaking Biology News(10 mins):Mouse study: Natural birth may strengthen the immune system 2No extra mutations in modified stem cells, study finds 2No extra mutations in modified stem cells, study finds 3Hunting gives deer-damaged forests in state parks a shot at recovery 2
... 2013 AT&T * and NEC Corporation of ... workhorse among ruggedized 4G LTE smartphones , the ... equipped with AT&T Enhanced Push-to-Talk (EPTT)**, NEC ... is aimed at breaking productivity barriers to keep workforces ...
... anabolic agent for tissue-building and energy storage, promoting the ... inhibiting their breakdown and release into the circulatory system. ... entry into muscle tissue, where the glucose is metabolized ... exist in understanding the precise molecular mechanisms by which ...
... YORK , June 19, 2013  New York College of ... States Patent and Trademark Office for detecting biometric changes through ... have been injured, attacked or killed. This patent ... Agreements of New York College of Health Professions. ...
Cached Biology News:AT&T and NEC Introduce Ultra-Rugged Smartphone Designed for Hard Work, Real Life 2AT&T and NEC Introduce Ultra-Rugged Smartphone Designed for Hard Work, Real Life 3AT&T and NEC Introduce Ultra-Rugged Smartphone Designed for Hard Work, Real Life 4AT&T and NEC Introduce Ultra-Rugged Smartphone Designed for Hard Work, Real Life 5Breakthrough research of essential molecule reveals important targets in diabetes and obesity 2New Technology Using Biometrics Detects If Security Guards Are Attacked, Injured Or Killed 2New Technology Using Biometrics Detects If Security Guards Are Attacked, Injured Or Killed 3New Technology Using Biometrics Detects If Security Guards Are Attacked, Injured Or Killed 4
Rb anti-Occludin (C-term GST)...
anti-JNK2 Immunogen: Recombinant human JNK2 protein Accession Number: NM_002752 Quality Assurance: Routinely evaluated by immunoblot. Molecular Weight: 46 and/or 54 kDa Available ...
...
Prepared with distilled water. Yeast extract solution is autolyzed at 150 g/L....
Biology Products: