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Arena Pharmaceuticals Initiates Second and Third Pivotal Trials Evaluating Lorcaserin for the Treatment of Obesity
Date:12/13/2007

uticals(R) and Arena(R) are registered service marks of the company. "APD" is an abbreviation for Arena Pharmaceuticals Development.

Forward-Looking Statements

Certain statements in this press release are forward-looking statements that involve a number of risks and uncertainties. Such forward-looking statements include statements about the continuation of the Phase 3 program and development of lorcaserin, the significance of the inclusion in the BLOSSOM and BLOOM-DM trials of patients with FDA-defined valvulopathy and, in the case of the BLOOM-DM trial, with type 2 diabetes, the significance of the review of echocardiographic data, the timing of the Echocardiographic Safety Monitoring Board's month 12 review of echocardiographic data, the rate of valvulopathy in the BLOOM trial, the number of patients in the Phase 3 lorcaserin clinical trials, the timing, number, protocol, design, scope, cost and other aspects of the lorcaserin trials and studies, the completeness and usefulness of the expected database of lorcaserin data in exploring, evaluating and understanding lorcaserin, the growth and impact of obesity, the need for new treatment options to address obesity, the ability of lorcaserin to fulfill such need, the ability of data to support the use of lorcaserin, the tolerability, side effects, efficacy and the commercial and other potential of lorcaserin, the breadth of Arena's pipeline, Arena's strategy, preclinical and internal and partnered clinical programs, and about Arena's ability to develop compounds and commercialize drugs and other statements that are not historical facts. For such statements, Arena claims the protection of the Private Securities Litigation Reform Act of 1995. Actual events or results may differ materially from Arena's expectations. Factors that could cause actual results to differ materially from the forward-looking statements include, but are not limited to, Arena's planned clinical trials and studies may not proceed at t
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