Navigation Links
Arena Pharmaceuticals Initiates Second and Third Pivotal Trials Evaluating Lorcaserin for the Treatment of Obesity
Date:12/13/2007

tistically significant, progressive and dose-dependent weight loss over a 12-week period. Lorcaserin was generally well tolerated at all doses and had no apparent effects on heart valves or pulmonary artery pressure. A scheduled review by an independent Echocardiographic Safety Monitoring Board of unblinded echocardiograms performed after patients completed six months of dosing in the BLOOM trial confirmed that differences, if any, in the rates of FDA-defined valvulopathy in patients treated with lorcaserin and in the control group did not meet the board's predetermined stopping criteria.

About Obesity

Obesity affects tens of millions of people in the United States and poses a serious long-term threat to their health and welfare. The number of overweight and obese people has substantially increased over the past several decades. Approximately two-thirds of all adults in the United States are obese or overweight, and medical and related costs of obesity were more than $123 billion according to a 2005 report by the International Diabetes Federation. Being obese or overweight is associated with increased risk of a number of conditions, including heart disease, stroke, diabetes, cancer and osteoarthritis. Medical treatment options for obese and overweight people currently are limited.

About Arena Pharmaceuticals

Arena is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing oral drugs in four major therapeutic areas: cardiovascular, central nervous system, inflammatory and metabolic diseases. Arena's most advanced drug candidate, lorcaserin, is being investigated in a Phase 3 clinical trial program for the treatment of obesity. Arena's broad pipeline of novel compounds targeting G protein-coupled receptors, an important class of validated drug targets, includes compounds being evaluated independently and with its partners, Merck & Co., Inc. and Ortho-McNeil Pharmaceutical, Inc.

Arena Pharmace
'/>"/>

SOURCE Arena Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Arena Pharmaceuticals to Present at the Bear Stearns 20th Annual Healthcare Conference
2. Arena Pharmaceuticals Continues Phase 3 BLOOM Obesity Trial Following Independent Echocardiogaphic Data Safety Monitoring Board Review
3. Arena Pharmaceuticals Continues Phase 3 BLOOM Obesity Trial Following Independent Echocardiographic Data Safety Monitoring Board Review
4. Arena Pharmaceuticals Selected to Join New NASDAQ NeuroInsights Neurotech Index
5. Arena Pharmaceuticals to Present at Two Upcoming Investor Conferences
6. Arena Pharmaceuticals to Report Third Quarter 2007 Financial Results and to Host Conference Call and Webcast on Wednesday, October 17, 2007
7. Arena Pharmaceuticals Announces Third Quarter 2007 Financial Results
8. Arena Pharmaceuticals to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference
9. Arena Pharmaceuticals Appoints Phillip M. Schneider and Randall E. Woods to Board of Directors
10. Vion Pharmaceuticals Pays Interest on 7.75% Convertible Senior Notes
11. China Biopharmaceuticals Holdings Announces Second Quarter 2007 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... METTLER TOLEDO’s newly improved XS balance ... balances as well as a dual range microbalance ... new SmartPan™ weighing pan delivers results up to twice ... balances, ergonomic design details mean users no longer need ... long periods in front of the balance. Barbara Bienlein, ...
(Date:10/1/2014)... CHICAGO , Oct. 1, 2014 ... purity Mannose (USP/NF, EP), manufactured in the ... conditions.  "Mannose has long been recognized for playing ... is a growing body of evidence that media ... and consistency of protein glycosylation," according to Dr. ...
(Date:10/1/2014)... September 30, 2014 New applications of ... that have evolved in nature over millennia are featured ... materials for applications in biophotonics in the October ... The journal is published by SPIE, the international society ... Several of the peer-reviewed articles are accessible via open ...
(Date:10/1/2014)... Sept. 30, 2014 This report ... in US$ Million by the following Product ... Enzymes. Specific end-use segments also analyzed are ... The report provides separate comprehensive analytics ... Middle East, and Latin America. Annual estimates ...
Breaking Biology Technology:METTLER TOLEDO’s XS Balance Line Delivers Performance and Ergonomics To Safeguard Health in the Workplace 2METTLER TOLEDO’s XS Balance Line Delivers Performance and Ergonomics To Safeguard Health in the Workplace 3Pfanstiehl Launches cGMP-produced Mannose for Cell Culture Media Optimization & Glycoprotein Biosynthesis 2Biomimetic and bioinspired materials enable new healthcare options, reports Journal of Biomedical Optics 2Biomimetic and bioinspired materials enable new healthcare options, reports Journal of Biomedical Optics 3Global Specialty Enzymes Industry 2Global Specialty Enzymes Industry 3Global Specialty Enzymes Industry 4Global Specialty Enzymes Industry 5Global Specialty Enzymes Industry 6Global Specialty Enzymes Industry 7Global Specialty Enzymes Industry 8Global Specialty Enzymes Industry 9Global Specialty Enzymes Industry 10Global Specialty Enzymes Industry 11Global Specialty Enzymes Industry 12Global Specialty Enzymes Industry 13Global Specialty Enzymes Industry 14Global Specialty Enzymes Industry 15Global Specialty Enzymes Industry 16Global Specialty Enzymes Industry 17Global Specialty Enzymes Industry 18Global Specialty Enzymes Industry 19Global Specialty Enzymes Industry 20Global Specialty Enzymes Industry 21Global Specialty Enzymes Industry 22Global Specialty Enzymes Industry 23Global Specialty Enzymes Industry 24Global Specialty Enzymes Industry 25Global Specialty Enzymes Industry 26
... Virent , a University of Wisconsin-Madison spinoff working ... from the Department of Energy for continued research. , ,The ... and sugar in a one-step process as part of a ... of the problems of storing hydrogen, a highly explosive gas. ...
... for the 21st Century Act, commonly called Check 21, ... electronic check imaging. , ,Check 21, which will come ... the efficiency of the payments system by legalizing the ... the physical documents. Using the substitute check, banks are ...
... live in interesting times. Not so long ago, we IT practitioners may ... moons on them. What we did was a mystery to the rest ... magic trick gone bad, there was a huge puff of smoke on ... for all the world to see. , ,Somewhere in all of that, ...
Cached Biology Technology:Wisconsin firms make acquisitions for Check 21 readiness 2IT leadership is not just for CIOs anymore 2
(Date:9/30/2014)... Mediterranean each year, but its deep-blue waters host ... 1,000 alien species, including fish, crustaceans, and algae ... activities. In the open-access journal Frontiers in ... analyzed data from a new information system developed ... introduction of alien species has changed the native ...
(Date:9/30/2014)... watermelon, salmon, and strawberries all have in common? ... of chromosomes and are diploid, these organisms are all ... chromosomesseedless watermelon and salmon have 3 and 4 sets ... this might seem surprising, in fact most plant species ... over a century ago, but only recently, with the ...
(Date:9/30/2014)... Prenatal exposure to tetrachloroethylene (PCE) in drinking water ... abruption, according to a new study led by ... , The study, published in the journal ... 1,019 unexposed pregnancies among 1,766 women in Cape ... late 1960s to the early 1980s by the ...
Breaking Biology News(10 mins):Biodiversity in the Mediterranean is threatened by alien species 2Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 2Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 3Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 4Contaminated water linked to pregnancy complications, BU study finds 2
... an odd-looking mouse discovered through a U.S. government breeding program in ... set of ribs in its neck and nobody knew why. ... of California, San Francisco has now spilled the genetic secrets of ... new wrinkle in the genetic code an entirely unrecognized way ...
... to announce BIOLOGY OPEN (BiO), a new online only, ... of the biological sciences including cell science, developmental biology ... rapid publication for peer reviewed, scientifically sound observations and ... will address some big issues in publishing and is ...
... Two groups of small fish, one from a Caribbean island and ... fastest rates of evolution known in any organism, according to a ... found from Massachusetts to Venezuela -- and they are all pretty ... Davis graduate student working with Peter Wainwright, a professor of evolution ...
Cached Biology News:Mutant mouse reveals new wrinkle in genetic code, say UCSF scientists 2Mutant mouse reveals new wrinkle in genetic code, say UCSF scientists 3Announcing BIOLOGY OPEN from the Company of Biologists 2'Explosive' evolution in pupfish 2
... workstation offers precise 96 and 384-well transfers ... 100ul and 200ul disposable tips, the 96 ... and precision across a volume range from ... two positions that enable indexing into 384 ...
... Rabbit Tissue Arrays contain 60 rabbit tissue samples ... contains 4 unstained slides and 1 hematoxylin and ... slide contains 15 different tissues from 4 rabbit ... per slide. Each tissue sample (or core) is ...
A univariate (peak height or area) quantitative multi-component analysis package....
... The new, upgraded micro 10 represents ... that brings many of the benefits of ... of the small benchtop dispenser. Dispensing accurate ... well, the micro 10 has unique advantages ...
Biology Products: