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Arena Pharmaceuticals Continues Phase 3 BLOOM Obesity Trial Following Independent Echocardiogaphic Data Safety Monitoring Board Review
Date:9/11/2007

ce. Also, Arena has proposed to the FDA to continue conducting patient echocardiograms in these additional pivotal studies. Expanding the echocardiogram program beyond the BLOOM trial is prudent as part of the effort to establish a robust database to thoroughly evaluate and understand lorcaserin's safety profile.

"There is a clear need for novel, safe and effective treatment options to address the growing problem of obesity, which poses a serious long-term threat to the health and welfare of tens of millions of people in the United States alone, including the majority of people with type 2 diabetes," said William R. Shanahan, M.D., Arena's Vice President and Chief Medical Officer. "This safety review of the lorcaserin echocardiographic data allows for continued development of this promising compound, which seeks to address weight loss by selectively stimulating a specific area of the brain associated with the control of satiety and metabolism. I am hopeful that future data will prove this approach to be the type of additional tool we need in the fight against obesity."

Scheduled Conference Call

Arena will host a conference call and webcast to discuss the results, and to provide a corporate update today, Tuesday, September 11, 2007 at 8:30 a.m. Eastern Time (5:30 a.m. Pacific Time). Jack Lief, President and Chief Executive Officer, Dominic P. Behan, Ph.D., Senior Vice President and Chief Scientific Officer and William R. Shanahan, M.D., Vice President and Chief Medical Officer will host the conference call.

The conference call may be accessed by dialing 800.901.5247 for domestic callers and 617.786.4501 for international callers. Please specify to the operator that you would like to join the "Lorcaserin BLOOM trial update." The participant code for the call is 56686107. The conference call will be webcast live under the investor relations section of Arena's website at http://http://www.a
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SOURCE Arena Pharmaceuticals
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