Ardea Biosciences to Present Data on Lead MEK Inhibitor, RDEA119, at Digestive Disease...( SAN DIEGO May 14 /- Ardea Bioscie...)
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Ardea Biosciences to Present Data on Lead MEK Inhibitor, RDEA119, at Digestive Disease Week 2008
Date:5/14/2008
SAN DIEGO, May 14 /PRNewswire-FirstCall/ -- Ardea Biosciences, Inc.
(Nasdaq: RDEA) today announced that preclinical data will be presented on
the Company's lead mitogen-activated ERK kinase (MEK) inhibitor, RDEA119,
at Digestive Disease Week (DDW) 2008 in San Diego.
The oral presentation details are as follows:
Date/Time: Tuesday, May 20, 2008 at 3:30 p.m. Pacific Time
Abstract Title: RDEA119, a Potent and Highly Selective MEK Inhibitor
Ameliorates Murine Colitis
Session Title: Novel Therapeutic Agents in Experimental Colitis
Location: 28DE: San Diego Convention Center
About Ardea Biosciences
Ardea Biosciences, Inc. of San Diego, California, is a biotechnology
company focused on the discovery and development of small-molecule
therapeutics for the treatment of HIV, cancer and inflammatory diseases,
including gout. We have four drug candidates in clinical trials and several
others in preclinical development and discovery. Our most advanced drug
candidate is RDEA806, a non-nucleoside reverse transcriptase inhibitor
(NNRTI), which is in a Phase 2a study for the treatment of HIV. We have
evaluated our second generation NNRTI, RDEA427, for the treatment of HIV in
a human micro-dose pharmacokinetic study and have selected it as a
development candidate. We are also investigating RDEA806 for the treatment
of gout. We are evaluating our lead MEK inhibitor, RDEA119, in a Phase 1
study in advanced cancer patients, as well as in a Phase 1 study in normal
healthy volunteers for the treatment of inflammatory diseases. We have
evaluated our second generation MEK inhibitor, RDEA436, for the treatment
of cancer and inflammatory diseases in a human micro-dose pharmacokinetic
stud
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