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Ardea Biosciences Reports Recent Accomplishments and Second Quarter 2011 Financial Results
Date:8/5/2011

SAN DIEGO, Aug. 5, 2011 /PRNewswire/ -- Ardea Biosciences, Inc. (Nasdaq: RDEA), a biotechnology company focused on the development of small-molecule therapeutics for the treatment of serious diseases, today reported recent accomplishments and financial results for the second quarter and six months ended June 30, 2011.

"Since our last quarterly update, we presented exciting initial results from the ongoing extension portion of our Phase 2b trial of lesinurad demonstrating high rates of sustained uric acid lowering and patient response over week 28 of the study at all doses," commented Barry D. Quart, PharmD, president and chief executive officer. "These results, together with the impressive efficacy and safety profile established in previous studies, position lesinurad very well for our upcoming Phase 3 clinical studies."

Recent Accomplishments and Important Upcoming Events

  • In May 2011, we presented additional positive results from the primary dosing and ongoing extension periods of our Phase 2b study (Study 203) adding lesinurad to allopurinol in patients who did not achieve target serum urate (sUA) levels on allopurinol alone, as well as other preclinical and clinical data from our lesinurad development program, at the Annual European Congress of Rheumatology hosted by the European League Against Rheumatism (EULAR).  Highlights included:
  • Results from the ongoing, blinded extension portion of Study 203 showed that 91 percent of patients receiving lesinurad in combination with allopurinol achieved sUA levels below the clinically important target of 6 mg/dL after 28 weeks of dosing. In addition, continued reductions in sUA were observed beyond the initial 28 days of dosing with the majority of the responding patients remaining on the 200 mg dose of lesinurad thus far in the extension portion. The combination has been generally well toler
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