Navigation Links
Ardea Biosciences Announces Positive End-of-Phase 2 Meetings with FDA for Lesinurad
Date:9/7/2011

will evaluate the effect of adding lesinurad to allopurinol in patients who do not reach target sUA levels on allopurinol alone. The interventional study will also help identify allopurinol-intolerant patients who would be eligible for the Company's Phase 3 study of lesinurad monotherapy for patients in whom allopurinol is contraindicated. A Phase 3 study of lesinurad in combination with febuxostat is also planned.

"We are very gratified with the positive outcome and clear feedback from the FDA at our End-of-Phase 2 meetings," commented Barry D. Quart, PharmD, Ardea's president and chief executive officer. "We were also very pleased to have recently initiated our allopurinol interventional trial, as it is an important first step in the efficient and effective conduct of our overall Phase 3 program for lesinurad.  It should help expedite overall enrollment in the main portion of our Phase 3 program by enabling us to identify ahead of time eligible patients to participate in our studies."

About Hyperuricemia and Gout

Gout is a painful, debilitating and progressive disease caused by abnormally elevated levels of uric acid in the blood stream.  This leads to the deposition of painful, needle-like uric acid crystals in and around the connective tissue of the joints and in the kidneys, resulting in inflammation, the formation of disfiguring nodules, intermittent attacks of severe pain and kidney damage.  In addition, evidence suggests that the chronic elevation of uric acid associated with gout, known as hyperuricemia, may also have systemic consequences, including an increased risk for kidney dysfunction and cardiovascular disease.

In 2008, approximately 8.3 million patients in the U.S., 9 million patients in the European Union and 2.9 million patients in Japan had been diagnosed with gout.  Gout is the most common form of inflammatory arthritis in men over the age of 40 and represents a significant unmet medical n
'/>"/>

SOURCE Ardea Biosciences, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Ardea Biosciences Reports Recent Accomplishments and Second Quarter 2011 Financial Results
2. Ardea Biosciences to Present at Upcoming Investor Conferences
3. Ardea Biosciences Announces Data on MEK Inhibitor BAY 86-9766 (RDEA119) to be Presented at 2011 American Society of Clinical Oncology Annual Meeting
4. Ardea Biosciences Reports Recent Accomplishments and Announces First Quarter 2011 Financial Results
5. Ardea Biosciences Reports Recent Accomplishments and Announces Fourth Quarter and Full-Year 2010 Financial Results
6. Ardea Biosciences Announces Exercise in Full of Overallotment Option for Common Stock Offering
7. Ardea Biosciences Prices Public Offering of Common Stock
8. Ardea Biosciences Announces Positive Top-Line Results from Phase 2b Combination Study of RDEA594 in Allopurinol-Refractory Gout Patients
9. Ardea Biosciences to Present at Two Upcoming Investor Conferences
10. Ardea Biosciences Awarded a $733,438 Grant from the U.S. Government Under the Patient Protection and Affordable Care Act
11. Ardea Biosciences to Present at the Oppenheimer 21st Annual Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... This is a professional and in-depth ... Resin industry in Global and China.The report provides ... applications and industry chain structure. Global market analysis ... a focus on history, developments, trends and competitive ... international and Chinese situation is also offered. , ...
(Date:9/23/2014)... (PRWEB) September 23, 2014 Erlab ... laboratory personnel since 1968 and Burdinola, supplier of laboratory ... a new filtered fume hood. , By ... fume hood, Burdinola will now offer an innovative solution ... wide range of chemicals, best-in-class detection technology, and communication ...
(Date:9/23/2014)... Proove Biosciences , the commercial and research leader ... association between specific genes and patients’ predisposition to anxiety ... Congress’ 27th Annual Scientific Program in Orlando, Florida. ... ‘Embracing Change.’ Mental health, and healthcare as a whole, ... presented by the Affordable Care Act to the growing ...
(Date:9/23/2014)... , Sept. 23, 2014 Research ... "Proteomics Markets for Research and IVD Applications ... report to their offering. ... proteomics applications, both in their research use and ... including the study of the structure and function ...
Breaking Biology Technology:Phenolic Resin Industry (International, China) Development Policy and Plan Now Available at ReportsnReports.com 2Erlab Partners with Burdinola to Deliver an Innovative Filtered Fume Hood 2Proove Biosciences Will Be Exhibiting New Genetic Research at the 27th Annual US Psych Congress Scientific Program 2Proove Biosciences Will Be Exhibiting New Genetic Research at the 27th Annual US Psych Congress Scientific Program 3Proteomics Markets for Research and IVD Applications (Mass Spectrometry, Chromatography, Microarrays, Electrophoresis, Immunoassays, Other Technologies) 2Proteomics Markets for Research and IVD Applications (Mass Spectrometry, Chromatography, Microarrays, Electrophoresis, Immunoassays, Other Technologies) 3Proteomics Markets for Research and IVD Applications (Mass Spectrometry, Chromatography, Microarrays, Electrophoresis, Immunoassays, Other Technologies) 4
... Md. and BEIJING, Jan. 10, 2012 The global ... as Aeras and the China National Biotec Group (CNBG) ... develop new tuberculosis (TB) vaccines. The agreement between the ... largest biotechnology corporation in China signals a commitment by ...
... A superlens would let you see a virus in a drop ... It might, says Durdu Guney, make ultra-high-resolution microscopes as commonplace as ... a superlens, also known as a perfect lens, though people are ... so-called diffraction limit, so even the best won,t usually let us ...
... . , Scientists at Universidad Carlos III ... have joined efforts to develop new materials for thermonuclear ... oxide dispersion-strengthened, reduced-activation steel for the reactor structure. , ... the current energy crisis. It is produced when ...
Cached Biology Technology:Aeras and CNBG Sign Agreement on Tuberculosis Vaccine R&D 2Aeras and CNBG Sign Agreement on Tuberculosis Vaccine R&D 3Almost perfect: A breakthrough in superlens development 2New material for thermonuclear fusion reactors 2New material for thermonuclear fusion reactors 3
(Date:9/23/2014)... whose turn it is to do the washing up, negotiating ... as many students returning to university for the new ... a house can be a tricky business. , And now ... that new technology to allow people to monitor their energy ... the tension. , The study by a team of technology ...
(Date:9/23/2014)... California , 23 de septiembre de ... lanzamiento del Sistema 1290 Infinity II LC, ... de Infinity en su portafolio de cromatografía ... científicos y directores de laboratorio que alcancen ... excepcional, facilidad de uso y capacidad de ...
(Date:9/22/2014)... 2014 A new American Cancer Society study suggests ... (SNAP), previously known as the food stamp program, ... eligible non-participants. The authors say the findings emphasize ... the dietary quality of SNAP participants. , The ... households with the resources to obtain a nutritionally ...
Breaking Biology News(10 mins):Smart meters could cause conflict for housemates, study shows 2Smart meters could cause conflict for housemates, study shows 3Agilent Technologies anuncia el lanzamiento del Sistema 1290 Infinity II LC 2Agilent Technologies anuncia el lanzamiento del Sistema 1290 Infinity II LC 3Federal food program puts food on the table, but dietary quality could be improved 2
... by the Smithsonian Institution has completed a new study ... a 3-foot-tall, 18,000-year-old hominin skeleton, discovered four years ago ... one of the most striking confirmations of the original ... one of the oldest human migrations to Asia. The ...
... 20, 2007) Fifteen students mentored by members of the ... receive the 2007ASPB Summer Undergraduate Research Fellowships (SURF). The ... to his or her research project for a 10-week ... to the mentor for lab supplies, a free student ...
... virus first struck New York City in 1999, news ... health officials alike, showing that even affluent, urban societies ... has been widely studied, there is still little known ... urban and rural areas. Assistant professor at the ...
Cached Biology News:New research sheds light on 'Hobbit' 2ASPB announces Summer Undergraduate Research Fellowship 2007 recipients 2ASPB announces Summer Undergraduate Research Fellowship 2007 recipients 3UGA Odum School of Ecology professor receives grant to study West Nile Virus in NYC 2
Human LAIR2 Biotinylated Affinity Purified PAb...
... The mycobacteria in Complete Freund's ... the injection site which enhances the immuneresponse. ... is used for the initial injections; Incomplete ... boosts. Antigens (preferably in saline) are typically ...
2,4-Dinitrophenyl hapten is conjugated to Human Serum Albumin (HSA) protein through lysine....
Alexa Fluor 350/488/594 Filter Set (Semrock Brightline) *mounted* *Zeiss Axio AF...
Biology Products: