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Ardea Biosciences Announces Data on MEK Inhibitor BAY 86-9766 (RDEA119) to be Presented at 2011 American Society of Clinical Oncology Annual Meeting
Date:5/19/2011

SAN DIEGO, May 19, 2011 /PRNewswire/ -- Ardea Biosciences, Inc. (Nasdaq: RDEA) today announced that data from a completed, multi-center, Phase 1, monotherapy, dose-escalation study of BAY 86-9766 in advanced cancer patients will be presented in an Oral Abstract Session at the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, Illinois on Sunday, June 5, 2011.

Presentation details are as follows:Presentation Title:

Safety, Pharmacokinetics, and Pharmacodynamics Results From a Phase 1 Trial of BAY 86-9766 (RDEA119), a MEK Inhibitor, In Patients with Advanced Cancer Session Type/Title:

Oral Abstract Session: Developmental Therapeutics – Experimental Therapeutics Author/Presenter:

Colin Weekes, MD, PhD – Assistant Professor, Division of Medical Oncology, University of Colorado School of MedicineAbstract ID:

3007Date/Time:

Sunday, June 5, 2011 from 9:30 AM – 12:30 PM CDTAbout BAY 86-9766BAY 86-9766 (RDEA119) is a potent and highly selective inhibitor of mitogen-activated ERK kinase (MEK) for the treatment of cancer being developed under a global license agreement with Bayer Healthcare (Bayer). Preclinical and clinical data suggest that BAY 86-9766 has favorable properties, including once-daily oral dosing and excellent selectivity. In addition, BAY 86-9766 has been shown to suppress tumor cell growth in vitro and in vivo. Preclinical in vitro and in vivo oncology studies of BAY 86-9766 have demonstrated significant potential synergy across multiple tumor types when used in combination with other anti-cancer agents, including sorafenib (Nexavar®; Bayer, Onyx Pharmaceuticals, Inc.).

About Ardea Biosciences, Inc.Ardea Biosciences, Inc., of San Diego, California, is a biotechnology company focused on the development of small-molecule therapeutics for the treatment of serious diseases. Lesin
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SOURCE Ardea Biosciences, Inc.
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