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Ardea Biosciences Announces Changes to Research Management
Date:10/5/2007

- Dr. Jean-Luc Girardet Promoted to Vice President, Research Operations

- Dr. Patrick O'Connor to Establish a New Non-Profit Foundation

CARLSBAD, Calif., Oct. 5 /PRNewswire-FirstCall/ -- Ardea Biosciences, Inc. (OTC Pink Sheets: ARDC), a company focused on the discovery and development of small-molecule therapeutics for the treatment of viral diseases, cancer and inflammatory diseases, today announced changes to its research management. Dr. Jean-Luc Girardet has been named Vice President, Research Operations. Dr. Girardet will be responsible for implementing the Company's drug discovery programs. Dr. Girardet was previously Senior Director, Discovery Logistics. Prior to joining Ardea, he led HCV and HIV chemistry project teams and managed the Process Chemistry function at Valeant Pharmaceuticals.

Patrick O'Connor, Ph.D. will establish a new non-profit foundation focused on drug discovery and development for neglected diseases in developing countries. This new enterprise will leverage early discovery assets from the Ardea Biosciences' portfolio for neglected diseases in developing countries. To establish this new enterprise, Patrick O'Connor will transition from his current role as Chief Scientific Officer at Ardea Biosciences to a consultancy role to the Company on drug discovery and development.

"Jean-Luc's strong leadership and expertise in drug discovery will be critical as we grow our pipeline of proprietary drug candidates," said Barry D. Quart, PharmD, President and CEO. "Patrick's dedication to the search for novel treatments for some of the most important diseases impacting the developing world is a testament to his character. Although Patrick's day-to-day participation in our activities will be reduced, he will remain an important part of the Ardea family as our Chief Scientific Strategist and the scientific leader of our oncology drug discovery programs."

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