Arctic is pleased to announce that substantive scientific advances from leading academic institutions are being incorporated into the next generation of the Macula Risk test, Macula Risk® NXG. Seven (7) novel markers from three large impactful bodies of work from the foremost researchers in this field(8,9,10), including the cholesterol metabolic markers (CETP, LPL, LIPC and ABCA1), the complement factor I gene (CFI) and the intracellular matrix genes (COL8A1 and TIMP3), are being added to the algorithm along with age, smoking, BMI and the clinical status of AMD. Validated risk determinations of two large and independent populations have demonstrated the ability of this model to accurately predict progression to advanced AMD within 10 years (AUC=0.895), with a sensitivity and specificity each greater than 80%3. This is a level of performance unprecedented in the field of AMD risk assessment.
ArcticDx Inc. is a molecular diagnostic company with expertise in the design, development and commercialization of validated molecular diagnostic tests. Our business model is focused towards the rapid commercialization of Intellectual Property (IP) from international gene discovery programs. We combine the work of academic strategic partners (i.e. Cancer Care Ontario ARCTIC project - Colorectal Cancer; University of Michigan - Macular Degeneration) with our international commercialization pr
|SOURCE ArcticDx Inc.|
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