Navigation Links
Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Dose-Ranging Field Study in Client-Owned Dogs with Osteoarthritis
Date:11/20/2013

KANSAS CITY, Kan. and BOSTON, Nov. 20, 2013 /PRNewswire/ -- Aratana Therapeutics, Inc. (NASDAQ: PETX), a biopharmaceutical company focused on the licensing, development and commercialization of innovative medications for pets, today announced positive results from its dose-ranging study of AT-001, the company's innovative drug for treating pain in dogs with osteoarthritis.  In the study, dogs receiving AT-001 demonstrated improvements in pain assessment scores that were statistically significant compared to placebo (p<0.05) at a once-daily dose.  Aratana expects to move AT-001 forward into the pivotal field effectiveness study in 2014, and then, if the results of the pivotal effectiveness study are favorable, into commercialization upon approval, which is anticipated to be in 2016.

The blinded, placebo-controlled, multi-center dose-ranging study of AT-001 enrolled in excess of 300 client-owned dogs with osteoarthritis.  Dogs were randomized equally into three groups treated with AT-001 (two once per day dose groups and one twice per day dose group) and one group treated with placebo.  Dogs were dosed for 28 days, and effectiveness was determined by a standard protocol utilizing a validated owner-assessed pain score.  Aratana has selected a once-daily dose for further development.

Ernst Heinen, DVM, Ph.D., Head of Drug Evaluation and Development for Aratana Therapeutics, stated, "We are very pleased with these results, which allow us to move forward confidently with a dose of AT-001 that appears safe at therapeutic levels for dogs with osteoarthritis pain."

Steven St. Peter, M.D., President and Chief Executive Officer of Aratana Therapeutics, added, "We believe AT-001 has the potential
'/>"/>

SOURCE Aratana Therapeutics, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Aratana Therapeutics to Present at Two Upcoming Investor Conferences
2. Aratana Therapeutics Inc. to Report Third Quarter 2013 Financial Results
3. Aratana Therapeutics to Report Second Quarter 2013 Financial Results
4. Aratana Therapeutics Announces Full Exercise of Over-Allotment Option
5. Aratana Therapeutics Adds To Drug Development Team
6. Aratana Closes $10 Million Non-Dilutive Financing with Square 1 Bank
7. Aratana Therapeutics Adds Product Manufacturing Expertise with the Appointment of Two Senior Executives
8. Aratana Therapeutics Appoints Craig Tooman to Board of Directors
9. Aratana Therapeutics Completes $15 Million Series B Financing
10. Northwest Biotherapeutics Announces Pricing Of Public Offering Of Common Stock And Warrants
11. Jade Therapeutics Elects Veteran Life Science Entrepreneur Dinesh Patel, Ph.D., to its Board of Directors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... The North American crystal oscillator market ... with analysis and forecast of revenue. This market was ... to reach $623.6 million by 2018, at a CAGR ... the TOC of the North American crystal oscillator market ... provided. This also provides a glimpse of the segmentation ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Involution ... the release of a new infographic, Understanding Ebola ... create a beautifully designed, easy to follow informative tool ... areas of outbreak, symptoms and prevention. , "As the ... that the 2014 Ebola outbreak represents not only a ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Currently ... Sartorius, A & D Weighing, Rice Lake, and ... Semi-Micro Balance . The Sartorius CPA Semi-Micro Balance ... affordable high-quality, precise, and user-friendly laboratory balance. , ... laboratory equipment, their laboratory balances are well known ...
(Date:10/22/2014)... SC (PRWEB) October 22, 2014 ... of its cardiovascular pharmacogenetics menu, which enables healthcare ... outcomes. With PCLS’s evidence-based results, healthcare providers ... and optimize their therapy, while minimizing risks for ... the U.S., according to the FDA [1] more ...
Breaking Biology Technology:The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 2The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 3The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 4Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2Pipette.com Launches the Addition of Sartorius CPA Semi-Micro Balance to Their Product Portfolio with Special Promotional Pricing 2Pipette.com Launches the Addition of Sartorius CPA Semi-Micro Balance to Their Product Portfolio with Special Promotional Pricing 3PCLS Announces Expansion of Cardiovascular Pharmacogenetic Testing Menu 2PCLS Announces Expansion of Cardiovascular Pharmacogenetic Testing Menu 3
... as a way to, protect the lives of the nation,s ... ... Poisoning, IRVINE, Calif., Feb. 19 Masimo (Nasdaq:,MASI), the inventor of ... the National Fire Protection,Association (NFPA) has included Carbon Monoxide (CO) screening by ...
... CAMBRIDGE, Mass.--MIT researchers have explained why two mutations in ... transmission in humans during the 1918 pandemic outbreak that ... showed that the 1918 influenza strain developed two mutations ... it to bind tightly to receptors in the human ...
... PHOENIX, Feb. 18 First Choice Professionals, LLC.,today ... expanding,Applications Services business unit. Mark will join FCP ... Mark brings thirteen years of Healthcare IT thought ... was responsible for the,Management of systems support at ...
Cached Biology Technology:National Fire Protection Association (NFPA) Sets New National Standard for CO Screening by Pulse CO-Oximetry(TM) 2National Fire Protection Association (NFPA) Sets New National Standard for CO Screening by Pulse CO-Oximetry(TM) 3National Fire Protection Association (NFPA) Sets New National Standard for CO Screening by Pulse CO-Oximetry(TM) 4MIT explains spread of 1918 flu 2FCP Welcomes Mark Scherling 2
(Date:10/18/2014)... and stress-related psychiatric disorders are associated with ... molecular mechanisms underlying this relation are unknown. ... development of targeted preventive strategies and new ... This work is presented at the European ... an international group of researchers from Germany ...
(Date:10/17/2014)... Copenhagen have shown for the first time how bacteria ... patients, giving them the opportunity to get tremendous insights ... The study also discovered the bacterial growth in chronic ... or slowed down by the immune cells. The researchers ... helped "suffocate" the bacteria, forcing the bacteria to switch ...
(Date:10/16/2014)... thinking on how the bowel lining develops and, in ... cancer starts. , The researchers produced evidence that stem ... that are a feature of the bowel lining, and ... development, a controversial finding as scientists are still divided ... technologies, Dr Chin Wee Tan and Professor Tony Burgess ...
Breaking Biology News(10 mins):Researchers find why depression and aging linked to increased disease risk 2Scientists opens black box on bacterial growth in cystic fibrosis lung infection 2Cryptic clues drive new theory of bowel cancer development 2
... been described as "molecular switches" and play a role ... and multiple other common cellular functions. Understanding ... cellular mechanisms related to cancer, which is fundamentally a ... rapidly, multiply and migrate into inappropriate places in the ...
... pain (or lumbago) is a common ailment often triggered by something ... to remedy the situation? An exercise machine designed specifically for back ... in the Journal of the American College of Sports Medicine ... help the development and endurance of back muscles, you must focus ...
... his groundbreaking research focusing on population biology and ecology ... researcher Dr. David Secor has been awarded the University ... for Excellence. As a fisheries biologist, a large ... that often have management conflicts: striped bass, bluefin tuna, ...
Cached Biology News:Research pinpoints action of protein linked to key molecular switch 2Exercise therapy for low back pain 2UMCES fisheries biologist Dr. David Secor receives USM Regent's Faculty Award for research 2
Mouse monoclonal [PRMT5-21] to PRMT5 ( Abpromise for all tested applications). entrezGeneID: 10419 SwissProtID: O14744...
Mouse TrkC Affinity Purified Polyclonal Ab...
Mouse MMP-24 (MT5-MMP) MAb (Clone 143908)...
TMB Slow Kinetic One Component HRP Microwell Substrate, 1 L...
Biology Products: