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Appointment of Chief Executive Officer
Date:9/19/2011

LONDON, September 20, 2011 /PRNewswire/ --

Silence Therapeutics plc (AIM: SLN) ("Silence", the "Group" or the "Company"), a leading global RNA interference (RNAi) therapeutics company, today announces the appointment of Thomas Christély as Chief Executive Officer with immediate effect. He will be based at Silence's facility in Berlin.

Thomas Christély (aged 51) brings more than 20 years experience in corporate and business development and finance. He was instrumental in the merger of Silence Therapeutics AG (formerly Atugen AG) with Silence Therapeutics plc (formerly SR Pharma plc) and admission to the Alternative Investment Market of the London Stock Exchange.   His track record includes concluding major collaborations with AstraZeneca, Pfizer, Dainippon Sumitomo, multiple financing transactions as well as M&A, divestments and strategic restructurings. He joined Atugen AG in 2001 as Chief Financial Officer and became Chief Operating Officer in 2002 before being appointed its Chief Executive Officer in 2006. Prior to joining Silence, Thomas was Senior VP and CFO at OXO Chemie AG, a Swiss pharmaceutical company, and founded its subsidiary OXO Chemie Inc. in San Francisco, where he stayed from 1997 until 2000.  Mr. Christély was managing partner of the investment firm Löschen & Partner, Hamburg/Moscow, from 1992 to 1995 and worked in mergers & acquisitions at Enskilda Corporate Finance, London, from 1989 to 1992. After his studies in Hamburg and Geneva, he received degrees in Business Administration (equivalent to MBA) and Law from the University of Hamburg and was admitted as attorney-at-law. Thomas Christély is currently Non-executive Chairman of the Supervisory Board of Müller-Spreer AG, Hamburg, and CEO of Silence Therapeutics AG.  

Jerry Randall, Chairman of Silence Therapeutics, said: "After a thorough selection process of internal and external candidates, we a
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SOURCE Silence Therapeutics Plc
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