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Apieron, Inc. Announces FDA Clearance of the Insight(TM) eNO System to Assist Physicians with Patient Asthma Management
Date:3/17/2008

Physician's office system for measuring airway inflammation poised to

transform asthma management for improved control.

MENLO PARK, Calif., March 17 /PRNewswire/ -- Apieron, Inc. (http://www.apieron.com) announced today that the Insight eNO system has received clearance to market by the U.S. Food and Drug Administration.

The Insight eNO system measures exhaled nitric oxide (eNO), which is a well-established indicator of airway inflammation and asthma control. The Insight system is a highly accurate device, expressly designed for the physician's office. It is non-invasive, safe, easy to use, and provides results in less than a minute. Apieron's unique biosensor detects trace amounts of nitric oxide molecules in a single human breath utilizing a proprietary technology. Current methods and techniques used to diagnose, monitor and treat asthma are costly, time-consuming and cumbersome. Physician office measurement of eNO is a much-awaited breakthrough in medical technology that provides physicians with a reliable tool to measure their patients' respiratory inflammation better than ever before. Measurement of eNO has also been shown to optimize medication therapy and improve compliance among patients with asthma.

William Berger, M.D., Clinical Professor of Pediatrics, University of California, Irvine, and Mission Viejo Medical Center, Mission Viejo, California, stated, "In clinical studies with the Apieron Insight eNO monitor, I found the ability to easily and accurately measure eNO in the physician's office to be a major advancement in my care for patients with persistent asthma."

It is estimated that more than 20 million people in the U.S. suffer from asthma, making it one of the most common and costly of all diseases. In fact, every day in America 40,000 people miss school or work due to asthma and 5,000 people go to the emergency room due to an asthma attack. One-quart
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SOURCE Apieron, Inc.
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