Navigation Links
Antigen Express Cancer Vaccine Highlighted in Expert Opinion on Biological Therapy
Date:9/19/2011

WORCESTER, Mass. and TORONTO, Sept. 19, 2011 /PRNewswire/ -- Generex Biotechnology Corporation's (OTCBB: GNBT) (www.generex.com) wholly-owned subsidiary, Antigen Express, Inc. (www.antigenexpress.com), today announced that AE37, a novel HER-2/neu-targeted vaccine for the treatment of breast, prostate, and other cancers, is reviewed in the September 2011 issue of Expert Opinion on Biological Therapy, a peer-reviewed, international journal publishing review articles and original papers on all aspects of biological therapy, providing expert opinion on the scope for future development.

(Logo:  http://photos.prnewswire.com/prnh/20110106/NY25057LOGO-b)

In the article titled "AE37: a novel T-cell-eliciting vaccine for breast cancer," senior author Col. George E. Peoples, M.D., F.A.C.S., Brooke Army Medical Center, focuses on the concept that AE37 vaccine's Ii-Key hybrid technology "has improved the potency of the AE37 vaccine to the point where it is capable of inducing immune responses even without immunoadjuvant," and that "preclinical and early clinical trials of the AE37 show potential promise for this CD4+ T-cell-eliciting vaccine in the adjuvant treatment of breast cancer."  

The article contrasts the unique ability of AE37 to stimulate CD4+ helper T cells with other therapeutic peptide vaccines that primarily stimulate CD8+ T cells, including E75 and GP2.  Another difference is that AE37 can be used to treat twice the patient population than either E75 or GP2. The article further outlines many of the trials conducted to date with AE37, including Phase I clinical trials in both breast and prostate cancer and the ongoing controlled, randomized, and single-blinded Phase II trial in breast cancer. While preliminary, the authors noted an approximate 40% reduction in the rat
'/>"/>

SOURCE Generex Biotechnology Corporation
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Generex Provides Update on Spinout of Antigen Express
2. Generex Announces Publication of Studies with the Mayo Clinic Confirming and Extending the Antigen Express Ii-Key Platform Technology
3. Generex Announces Publication on Application of Antigen Express Technology for Early Detection of Type 1 Diabetes
4. PharmAthene Submits White Paper to BARDA for Advanced Development Funding for SparVax(TM) - Novel Recombinant Protective Antigen Anthrax Vaccine
5. BARDA Announces Modification to Development Approach for Recombinant Protective Antigen Anthrax Vaccines
6. ImaginAb, Inc. and BZL Biologics, LLC Conclude Licensing Agreement for Imaging Rights to huJ591/Prostate-Specific Membrane Antigen (PSMA)
7. Antigen Discovery, Inc. Awarded Grant for Chlamydia Vaccine Development
8. ImmunoVaccine Technologies Licenses Immunotopes Breast, Ovarian and Prostate Cancer Antigens
9. Medicago succesfully expresses VLP antigen for A H1N1 strain
10. Pepscan Achieves a Breakthrough With CLIPS Immunogen Technology: Synthetic Peptide Antigen is Able to Induce Fully Functional Antibodies Against a Formerly Intractable GPCR Target CXCR7
11. PharmAthene Response to DHHS Request for Proposals for Recombinant Protective Antigen Anthrax Vaccine Deemed Technically Acceptable and Within Competitive Range for Procurement Consideration
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... , Dec. 19, 2014 Naurex Inc., ... novel drugs for diseases of the central nervous system, ... and chief executive officer, will present at the 33 ... presentation will take place at 3:00 p.m. PST on ... in San Francisco, Calif. ...
(Date:12/19/2014)... Bina Technologies, Inc. (Bina, Redwood ... have been acquired by Roche (SIX: RO, ROG; OTCQX: ... company that provides a big data platform for centralized ... for the academic and translational research markets.  Bina will ... continue to focus on development of their innovative genomic ...
(Date:12/19/2014)... , Dec. 19, 2014 Research and Markets ... addition of the "Technology Innovations in Smart ... http://photos.prnewswire.com/prnh/20130307/600769 ... Smart Fabrics" offers a detailed assessment on technological ... Key Findings: 1. The Smart ...
(Date:12/19/2014)... 2014 Today, TiFiber, Inc. ... production facility and future company headquarters in Fort ... new materials that safely and effectively control dangerous ... of its historic, strong support for manufacturing, but ... leading edge, technology-based companies such as TiFiber. ...
Breaking Biology Technology:Naurex to Present at 33rd Annual J.P. Morgan Healthcare Conference 2Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3Technology Innovations in Smart Fabrics (Technical Insights) 2Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 2Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 4
... - As part of a new National Science Foundation ... will work with some of the nation's top science museums ... the tiniest human fingers can't touch it. , ,The ... Minnesota , and the Exploratorium , San Francisco, are ...
... , ,Green Bay, Wis. MailFoundry , ... two new high availability MailFoundry anti-spam appliances, the ... $6,999 and $12,999, respectively, with no user, domain ... anti-spam appliances are powered by Solinus' MessageIQ email ...
... to grow new businesses, according to a national magazine. , ,Among ... Madison is sixth among mid-sized cities. , ,The trio of ... th . , ,The rankings are published in October's issue of ... on the list in 1999, according to Gov. Jim Doyle, who ...
Cached Biology Technology:Engineers help turn science into interactive exhibits 2Tech Digest: MailFoundry; API Software 2
(Date:12/10/2014)... , Dec. 9, 2014  Valencell, a leader ... is seeing a staggering demand from its licensees for ... Company revealed, is not solely coming from fitness and ... well. "A wearable is only as useful ... accuracy is the ultimate driver in long-term mass consumer ...
(Date:12/10/2014)... CIE San Diego has launched an innovative ... tissue that enhances care coordination among social service and ... information; earned a second $1 million grant from the ... aging in community and; will be recognized as a ... 4-6p. CIE San Diego today announced ...
(Date:12/10/2014)... , December 9, 2014 ... BCARD Platform   ... meeting scheduling solutions for business-to-business (B2B) events, today ... leader in mobile near-field communication (NFC), Bluetooth low ...      (Logo: http://photos.prnewswire.com/prnh/20140612/691055) , Jifflenow will ...
Breaking Biology News(10 mins):Wearable Technology Products Demand Highly Accurate Biometric Technology 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3
... international team led by a University of Cincinnati (UC) researcher ... host defenses in the body. The team, led by Malak ... microbiology department, analyzed the evolution over time of the community ... Strep A), a bacterium often found in the throat or ...
... can have undesirable outcomes on fish populations living in remote ... Hunt and Nigel Lester of the Ontario Ministry of Natural ... of Fisheries Management . The presence, location, ... point development on remote lakes in northern Ontario. Due to ...
... Understanding the key elements of biofuel combustion is ... fuels. And that,s exactly what researchers at Sandia ... journal Angewandte Chemie devotes its May 10 ... and Lawrence Livermore,s Charles Westbrook, which examines the essential ...
Cached Biology News:Research team shows how bacterial community evolves to survive 2Biofuel chemistry more complex than petroleum, say Sandia and Lawrence Livermore researchers 2
... The antibody is preadsorbed to remove any reactivity ... buffered aqueous glycerol solution A solution in ... and Ca 2+ ), pH 7.3 (+/- ... protease free) and 0.05% sodium azide A synthetic ...
... On-Demand Cytometry The Guava EasyCyte ... laser based multiparameter cytometer with built-in 96-well ... can screen plates of cells and compounds ... manipulating multiple tubes or having the carryover ...
Methylation analysis of gene promoters using bilsulfite treatment of DNA and comparative DNA sequence analysis. Probe design and PCR included....
... Fully automated, GLP-compliant Facility , Galaxy LIMS, ... , Highly experienced scientists ,We offer individual ... or full plasmids for single or double ... used when the DNA of interest is ...
Biology Products: