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Antibody Technologies and Attrition Rates -- an industry analysis 2013
Date:3/27/2013

Learn the influence of the target for the success rate of the selected antibody technology.

Table of Contents

1 Executive Summary and Discussion

2 Introduction 3 Methodology 4 Results 4.1 Use of antibody technologies

4.2 Attrition rates

4.3 Reasons for failure

4.4 Antibody generation technologies and targets

4.5 Antibody technologies and antibody formats

4.6 Parental animal species of in vivo generated antibodies

4.7 Immunoglobulin class and isotype vs. antibody technology

4.8 Antibody technology and therapeutic areas

4.9 Attrition rates of antibodies in therapeutic areas

4.10 Benchmark analysis: big pharma and biotech antibody technology preferences and attrition rates

5 Tables Table 1 Overall attrition rate of in vitro generated antibodies

Table 2 Overall attrition rate of in vivo generated antibodies

Table 3 Highest phase of active antibodies generated by in vitro technologies

Table 4 Highest phase of active antibodies generated by in vivo technologies

Table 5 Year of antibody failure for in vitro generated antibodies

Table 6 Year of antibody failure for in vivo generated antibodies

Table 7 Attrition rate of in vitro generated antibodies in the period 2006-2013

Table 8 Attrition rate of in vivo generated antibodies in the period 2006-2013

Table 9 Highest phase of failed antibodies generated by in vitro technologies

Table 10 Highest phase of failed antibodies generated by in vivo technologies

Tables 11 Reasons for failure of antibodies generated by in vitro technologies

Tables 12 Reasons for failure of antibodies generated by in vivo technologies

Table 13 Reasons for failure of humanized antibodies per phase

Tables 14 Targets of failed in vitro generated antibodies per technology

Tables 15 Targets vs. in vitro and in vivo antibody generation technologies

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