Navigation Links
Anthrax vaccine produces immunity with nanoparticles, not needles
Date:9/2/2007

ANN ARBOR, Mich. A vaccine against anthrax that is more effective and easier to administer than the present vaccine has proved highly effective in tests in mice and guinea pigs, report University of Michigan Medical School scientists in the August issue of Infection and Immunity.

The scientists were able to trigger a strong immune response by treating the inside of the animals noses with a nanoemulsion a suspension of water, soybean oil, alcohol and surfactant emulsified to create droplets of only 200 to 300 nanometers in size. It would take about 265 of the droplets lined up side by side to equal the width of a human hair.

The oil particles are small enough to ferry a key anthrax protein inside the nasal membranes, allowing immune-system cells to react to the protein and initiate a protective immune response. That primes the immune system to promptly fight off infection when it encounters the whole microbe.

Besides eliminating the need for needles, the nanoemulsion anthrax vaccine has another advantage, the researchers say: It is easy to store and use in places where refrigeration is not available.

An effective and easy-to-administer vaccine would be a valuable tool for health authorities dealing with any future attack in which a terrorist might spread anthrax microbes. The researchers say a nasal nanoemulsion-based anthrax vaccine, if it proves effective in humans, could be given easily to people even after they are exposed in an anthrax attack, along with antibiotics. With some diseases, vaccines given after exposure are used to boost the speed of the immune response.

Anthrax spores can remain in the environment or even in the lungs of exposed individuals for some time. Nasal vaccination could be given to build up immunity after anthrax exposure and improve the outcome of other treatments, says Anna Bielinska, Ph.D., the papers lead author and a scientist at the Michigan Nanotechnology Institute for Med
'/>"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. New nanotech approach could enable fast anthrax detection
2. New Mexico firm to make flu vaccine at Wisconsin BioManufacturing facility
3. Studies Offer New Insight into HIV Vaccine Development
4. Business Plan Contest produces successful grads
5. UW produces fast and flexible computer chip
6. Delivery of needles in the Capitol missed the point about stem-cell research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... New applications of structures and materials ... in nature over millennia are featured in a ... applications in biophotonics in the October issue of the ... published by SPIE, the international society for optics and ... peer-reviewed articles are accessible via open access. , “Biomimetic ...
(Date:10/1/2014)... San Francisco, California (PRWEB) October 01, 2014 ... grant from the National Science Foundation to expand their ... approaches to build and modify DNA. The Small Business ... help commercialize the “j5” technology under exclusive license from ... the Joint BioEnergy Institute , an LBNL laboratory ...
(Date:10/1/2014)... 2014 Industry leaders from ... engage around the theme, ,Commercial Opportunities in the Era ... Elsevier , a world-leading provider of ... host a gathering of some of the industry,s most ... healthcare today and in the future. The ...
(Date:9/30/2014)... German . ... have demonstrated a new kind of building block for ... chips could be based on three-dimensional arrangements of nanometer-scale ... of the semiconductor industry CMOS fabrication of silicon ... collaborators at the University of Notre Dame are exploring ...
Breaking Biology Technology:Biomimetic and bioinspired materials enable new healthcare options, reports Journal of Biomedical Optics 2Biomimetic and bioinspired materials enable new healthcare options, reports Journal of Biomedical Optics 3TeselaGen Receives $750k NSF SBIR Phase II Award 2TeselaGen Receives $750k NSF SBIR Phase II Award 3Elsevier Healthcare and Pharmaceutical Economics Conference 2014 To Convene Industry Leaders to Discuss Top Healthcare Business Issues 2Elsevier Healthcare and Pharmaceutical Economics Conference 2014 To Convene Industry Leaders to Discuss Top Healthcare Business Issues 3A new dimension for integrated circuits: 3-D nanomagnetic logic 2A new dimension for integrated circuits: 3-D nanomagnetic logic 3
...  Dyadic International, Inc. (OTC Pink: DYAI), a global biotechnology ... results for the first quarter ended March 31, 2012 ... will host a conference call at 5:00 p.m. Eastern ... http://photos.prnewswire.com/prnh/20110621/CL06708LOGO ) Those wishing to ...
... announced today the launch and immediate availability of the GS GType ... variation detection in four key human genes using the company,s ... sequence-based assays offer a new solution for cancer researchers investigating the ... RUNX1 genes, which are known to be associated with ...
... research team this week will present findings that they ... and breast cancer. "Cells have different ... chemical name for alcohol, that represent a potential risk ... pharmacology and toxicology at the Universidad Autonoma del Estado ...
Cached Biology Technology:Roche Launches 454 Sequencing Assays for High Sensitivity Genetic Variant Detection in Leukemia Samples to Drive Blood Cancer Research Worldwide 2Roche Launches 454 Sequencing Assays for High Sensitivity Genetic Variant Detection in Leukemia Samples to Drive Blood Cancer Research Worldwide 3Researchers Find Potential Link Between Drinking Alcohol And Breast Cancer 2Researchers Find Potential Link Between Drinking Alcohol And Breast Cancer 3
(Date:9/30/2014)... of tourists visit the Mediterranean each year, but ... underway on Earth. Almost 1,000 alien species, including ... other seas through human activities. In the open-access ... multinational team of researchers analyzed data from a ... to show how the introduction of alien species ...
(Date:9/30/2014)... Diego, have completed the first comprehensive numerical simulation of ... pixels in an image as data points for the ... researchers, led by J.S. Chen, the William Prager Professor ... at UC San Diego, presented their findings on the ... Pittsburgh this month. Chen also gave a keynote speech ...
(Date:9/30/2014)... most comprehensive assessment conducted by the Ocean Health ... of 100 in overall health. In addition, for ... and the 15 ocean regions beyond national jurisdiction ... a healthy climate, safeguarding biodiversity and providing sustainable ... of the index, a partnership led by scientists ...
Breaking Biology News(10 mins):Biodiversity in the Mediterranean is threatened by alien species 2First comprehensive meshfree numerical simulation of skeletal muscle tissue achieved 2Rating the planet's oceans 2Rating the planet's oceans 3
... by global warming, habitat loss, and other human impacts. ... functioning of ecosystems that humans depend on for goods and ... their primary functions with fewer species in them? After ... Earth, are scientists any closer to attaining these answers? ...
... Maps are great for showing where things are. ... Two Michigan State University professors have developed interactive maps ... By using GIS (geographic information systems) technology, they are ... losing access to fresh produce and balanced nutrition. ...
... Nottingham have joined forces with colleagues at Loughborough University and ... keep the mould at bay for longer. Cold plasma ... from wounds safely. It was a chance discovery that led ... cold plasma might also be useful in the food sector. ...
Cached Biology News:Will loss of plant diversity compromise Earth's life-support systems? 2Will loss of plant diversity compromise Earth's life-support systems? 3Will loss of plant diversity compromise Earth's life-support systems? 4Will loss of plant diversity compromise Earth's life-support systems? 5Mapping food deserts 2Keeping soft fruit 'fur-free' for longer 2
... On-Demand Cytometry The Guava ... blue laser based multiparameter cytometer with built-in ... you can screen plates of cells and ... of manipulating multiple tubes or having the ...
A flexible 24-48 hour DNA sequencing service. Samples may be shipped in standard 1.5mL tubes. Oligo synthesis and DNA preparation available. Read lengths up to 850 Phred 20 bases. Universal primers p...
... Agencourt offers single pass sequencing of ... is fueled by our high performance ... million Phred20 bases per day. The ... pass sequencing customers are rapid turnaround, ...
... Facility , Galaxy LIMS, Sophisticated Bioinformatics , ... scientists ,We offer individual sample sequencing of ... for single or double strand publication quality. ... DNA of interest is 1.3 to 7 ...
Biology Products: