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Angiotech's Licensee, Cook Medical, Announces CE Mark Approval and European Launch of the Zilver(R) PTX(R) Stent
Date:8/11/2009

s from Europe, Russia, Canada and Korea and demonstrated highly positive results. Failure rates for the device were very low, with only 8 percent of patients with de novo (new) lesions requiring a re-intervention to reopen the artery within the first 12 months - a rate significantly surpassing existing treatments for PAD in the SFA, such as balloon angioplasty and bare metal (non-drug-eluting) stents. Also, specific patient groups that are often difficult to treat, such as diabetics and patients with in-stent restenosis (i.e. patients whose previously placed bare metal stent had become blocked by scar tissue), were shown in the trial to benefit from the Zilver PTX. Importantly, the trial data indicates that the positive results achieved in the first year after treatment are largely maintained through the second year (24 months), an important clinical milestone.

About Peripheral Arterial Disease (PAD)

PAD is one of the fastest-growing and most pervasive diseases of our time, and it is estimated to affect 27 million individuals in Europe and North America.(1),(2),(3) Physical symptoms are only present in approximately one third of these individuals.(1),(4),(5) The 'silent' nature of this condition results in a significant number of patients being diagnosed only after their disease has progressed to a severe stage. Symptomatic PAD initially results in intermittent claudication (IC).(6) IC is characterized by muscle pain or fatigue in the legs that occurs during exercise and is relieved by a short period of rest. Further disease progression can result in critical limb ischemia (CLI)(6),(7), a severe condition associated with chronic pain, ulcers or gangrene due to severe arterial occlusion. In many countries, untreated PAD is the leading cause of leg amputation. Approximately 120,000 to 400,000 leg amputations occur annually due to PAD.(6),(7) Even when treated, current therapies such as bypass surgery and balloon angioplasty(8) are eit
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SOURCE Angiotech Pharmaceuticals, Inc.
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