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Angiotech announces completion of Bio-Seal(TM) clinical trial enrolment
Date:6/3/2008

VANCOUVER, June 3 /PRNewswire-FirstCall/ - Angiotech Pharmaceuticals, Inc. (NASDAQ: ANPI, TSX: ANP), a global specialty pharmaceutical and medical device company, today announced the completion of U.S. clinical trial enrolment for its novel Bio-Seal lung biopsy track plug.

"Our proprietary Bio-Seal product represents a potentially significant improvement in the technology used to diagnose lung cancer," said Dr. William Hunter, President and CEO of Angiotech. "We look forward to a review of the clinical trial data and are hopeful that the data will demonstrate a considerable reduction in the side effects related to lung biopsy procedures."

Bio-Seal is a novel technology designed to reduce the incidence of post-operative pneumothorax (collapsed lung) in patients who undergo lung biopsy procedures. The technology involves the placement of an expanding hydrogel plug along the biopsy needle track during the procedure, closing off the track to subsequent influx of air into the chest during respiration after the biopsy needle is withdrawn. The seal is airtight and the plug is absorbed into the body after healing of the puncture site has occurred

The primary endpoint of the Bio-Seal study is a reduction in the incidence of pneumothorax in patients undergoing lung biopsy procedures when compared with patients who do not receive the Bio-Seal product. The product has already received CE Mark approval and is available for commercial sale in the EU.

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SOURCE Angiotech Pharmaceuticals, Inc.
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