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Anesiva and Transcription Factor Therapeutics, Inc. Announce Licensing Agreement for Development and Commercialization of NF-kappa B Clinical Program
Date:6/5/2008

ientific meetings and are published in DeVry et al., (2007) Gut 56(4):524-33 "Non-viral delivery of nuclear factor-kappaB decoy ameliorates murine inflammatory bowel disease and restores tissue homeostasis." Avrina has been evaluated for safety, tolerability and anti- inflammatory drug effect in an exploratory, dose-ranging US Phase I clinical study for treatment of atopic dermatitis.

"TFT is extremely pleased to expand its development program to include the Avrina(TM) assets," said Ryan Rauch, President and COO of TFT. "Avrina(TM) may have the potential to provide durable, long-lasting inflammation reduction while providing patients with more convenient dosing regimens and fewer side effects. The extremely positive pre-clinical IBD data, together with the demonstrated safety and biological activity demonstrated in Anesiva's first- in-man studies with Avrina(TM), will help push our IBD program into the clinic in 2009. This will also help leverage our existing Atopic Dermatitis program that is scheduled to begin Phase II clinical testing in the U.S. in the second half of 2009."

About Anesiva and its Pipeline of Pain Products

Anesiva, Inc. is a late-stage biopharmaceutical company that seeks to be the leader in the development and commercialization of novel pharmaceutical products for pain management. The company has one FDA-approved product, Zingo, for the reduction of pain associated with peripheral venous access procedures in children ages 3 to 18. The second product in Anesiva's pipeline, Adlea(TM), has been shown to reduce pain after only a single administration for weeks to months in multiple settings in numerous mid-stage clinical trials for site- specific, acute and chronic, moderate-to-severe pain. Anesiva is based in South San Francisco, CA. For more information about Anesiva's leadership in the development of products for pain management, and an overview of the clinical challenges being addressed by its product candidates, go to '/>"/>

SOURCE Anesiva, Inc.
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Related biology technology :

1. Anesiva Announces First Quarter 2008 Financial Results
2. Anesiva Announces First Quarter 2008 Financial Results Conference Call and Webcast
3. Anesiva Announces Expansion of Zingo Agreement in Europe
4. Anesiva Announces New Zingo Marketing and Distribution Agreement
5. Anesiva Announces Submission of Supplemental New Drug Application for Zingo(TM) to Reduce Pain Associated With Needle Insertion Procedures in Adults
6. Anesiva Announces March 5, 2008 Presentation at Susquehanna Financial Group Healthcare Conference
7. Anesiva Announces Fourth Quarter and Year-End 2007 Financial Results and Provides 2008 Outlook
8. Anesiva Appoints Daniel Janney to Board of Directors
9. Anesiva Announces Fourth Quarter and Year End 2007 Financial Results Conference Call and February 2008 Conference Participation
10. Anesiva Announces Completion of Common Stock Offering
11. Anesiva Raises $45 Million in Common Stock Offering

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