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Analysis Provides New Insights Into Use of SYMLIN® in Patients With Type 1 Diabetes Using Insulin Pumps
Date:6/24/2011

SAN DIEGO, June 24, 2011 /PRNewswire/ -- Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN) today announced data from a new analysis characterizing the effects of SYMLIN® (pramlintide acetate) injection in patients with type 1 diabetes who used insulin pumps during two previously completed clinical studies. The data, which will be presented during a poster presentation at the 71st Scientific Sessions of the American Diabetes Association (ADA) in San Diego, demonstrated that SYMLIN helped reduce A1C (a measure of average blood sugar over three months), insulin use and body weight in patients with type 1 diabetes who used insulin pumps.

"On the backdrop of continued innovation and technical advances in insulin delivery and glucose monitoring, the number of patients with type 1 diabetes who are using insulin pumps has steadily increased in recent years – and is estimated to double over the next decade," said Steven Edelman, M.D., Professor of Medicine, Division of Endocrinology, Diabetes & Metabolism, University of California at San Diego and the Veterans Affairs Healthcare System of San Diego. "The findings from this analysis help us better understand the therapeutic benefit of SYMLIN as an adjunct therapy for patients with type 1 diabetes who use insulin pumps, as evidenced by reductions in A1C, insulin requirements (especially mealtime insulin) and weight. These data may provide additional insights for physicians' treatment decisions when considering other options for patients who are not achieving their targets with insulin pump use alone."

SYMLIN is a synthetic analog of human amylin, a naturally occurring hormone that is produced and released by beta cells in the pancreas, the same cells that produce and release insulin. In a healthy pancreas, the two hormones work together to help stabilize blood glucose levels. SYMLIN is approved for use as an adjunct tre
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SOURCE Amylin Pharmaceuticals, Inc.
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