Navigation Links
An organized approach to 3-D tissue engineering
Date:8/20/2013

Singapore, August 19, 2013 Researchers at the Institute of Bioengineering and Nanotechnology (IBN) have developed a simple method of organizing cells and their microenvironments in hydrogel fibers. Their unique technology provides a feasible template for assembling complex structures, such as liver and fat tissues, as described in their recent publication in Nature Communications1.

According to IBN Executive Director Professor Jackie Y. Ying, "Our tissue engineering approach gives researchers great control and flexibility over the arrangement of individual cell types, making it possible to engineer prevascularized tissue constructs easily. This innovation brings us a step closer toward developing viable tissue or organ replacements."

IBN Team Leader and Principal Research Scientist, Dr Andrew Wan, elaborated, "Critical to the success of an implant is its ability to rapidly integrate with the patient's circulatory system. This is essential for the survival of cells within the implant, as it would ensure timely access to oxygen and essential nutrients, as well as the removal of metabolic waste products. Integration would also facilitate signaling between the cells and blood vessels, which is important for tissue development."

Tissues designed with pre-formed vascular networks are known to promote rapid vascular integration with the host. Generally, prevascularization has been achieved by seeding or encapsulating endothelial cells, which line the interior surfaces of blood vessels, with other cell types. In many of these approaches, the eventual distribution of vessels within a thick structure is reliant on in vitro cellular infiltration and self-organization of the cell mixture. These are slow processes, often leading to a non-uniform network of vessels within the tissue. As vascular self-assembly requires a large concentration of endothelial cells, this method also severely restricts the number of other cells that may be co-cultured.

Al
'/>"/>

Contact: Nidyah Sani
nidyah@ibn.a-star.edu.sg
65-682-47005
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. DunhamTrimmer's, Bill Dunham and Mark Trimmer Are Invited Speakers at the Biopesticide Conference Organized by Informa in Raleigh, NC on August 7-8, 2013
2. Discovery in Nature elucidates immune cells in skin and supports novel vaccine approach
3. A Genetic Approach For Crohns And Colitis Disease Is Financed By The Jeffrey Epstein VI Foundation
4. New Approach to Growing Waste to Value Industry in United States
5. ARMGO Pharma, Inc. announces data which supports its Rycal program as a novel approach for the treatment of stress-induced cognitive disorders
6. ViThera Novel Approach Using Probiotics to Deliver Elafin Shows Promise as a Future Inflammatory Bowel Disease (IBD) Treatment
7. Trudeau Institute Awarded Grant to Investigate a New Approach to Treating Illnesses Caused by Weaponized and Antibiotic-Resistant Bacteria
8. Bottom-up approach provides first characterization of pyroelectric nanomaterials
9. Cost-Effective Approaches to Quality Distribution and Logistics for Temperature Sensitive Products
10. Local Dentist is Saving Lives with her Cutting Edge Approach to Dental Caries
11. Quantum Cures Announces Breakthrough Approach for Researchers Seeking Cures for Orphan and Rare Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/1/2015)... 2015 A new report by  ... will reach $22.4bn in 2019. That revenue forecast and ... Market Prospects 2015-2025 ,  published in March ... to provide forecasts and qualitative analyses of the antithrombotic ... consultancy in London, UK . It ...
(Date:5/1/2015)... Md. and RESEARCH TRIANGLE PARK, N.C. ... UTHR ) announced today that Roger Jeffs , ... provide an overview and update on the company,s business at ... in Boston, Massachusetts . The ... 3:30 PM Eastern Time, and can be accessed via a ...
(Date:4/30/2015)... Francisco, CA (PRWEB) April 30, 2015 Cytokinetics, ... the first quarter of 2015 were $4.4 million, compared to ... net loss for the first quarter was $8.9 million, or ... a net loss for the same period in 2014, of ... As of March 31, 2015, cash, cash equivalents and investments ...
(Date:4/30/2015)... 2015 The following is an open letter sent ... Cord Blood Corp (NYSE: CO ) from Jayhawk Capital. ... independent directors of China Cord Blood Corp (" China Cord ... per share from Golden Meditech Holdings Co Ltd ("Golden Med"). ... greatly benefit Golden Med and Mr. Kam, the Chairman of ...
Breaking Biology Technology:Antithrombotic Drugs: World Industry and Market Prospects 2015-2025 2Antithrombotic Drugs: World Industry and Market Prospects 2015-2025 3Antithrombotic Drugs: World Industry and Market Prospects 2015-2025 4Antithrombotic Drugs: World Industry and Market Prospects 2015-2025 5Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 2Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 3Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 4Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 5Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 6Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 7Cytokinetics, Incorporated Reports First Quarter 2015 Financial Results 8April 30, 2015 Open Letter to the Board of China Cord Blood Corp from Jayhawk Capital 2April 30, 2015 Open Letter to the Board of China Cord Blood Corp from Jayhawk Capital 3April 30, 2015 Open Letter to the Board of China Cord Blood Corp from Jayhawk Capital 4April 30, 2015 Open Letter to the Board of China Cord Blood Corp from Jayhawk Capital 5
... fighting to stay on budget as the first quarter of 2009 came to ... a field once thought immune to the troubles of the rest of the ... ... March 23, 2009 -- As the first quarter of 2009 came to a ...
... Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN ... its SCORPION(TM) multispecific therapeutic technology at the 100th ... Research (AACR) in Denver. The data presented demonstrated ... CD79BxDR SCORPION molecule, its differentiation from monospecific approaches, ...
... Do winery tasting rooms really help generate sales for ... Innovation Centre almost half of winery tasting room visitors ... visit. , "This research proves that the tasting room ... in future sales," said Dr. Isabelle Lesschaeve, research director, ...
Cached Biology Technology:The MedZilla Report: March 2009 Employment Outlook for Biotech/Pharma/Health 2The MedZilla Report: March 2009 Employment Outlook for Biotech/Pharma/Health 3The MedZilla Report: March 2009 Employment Outlook for Biotech/Pharma/Health 4Trubion Presents Preclinical Data on Its SCORPION(TM) Multispecific Therapeutics at the 2009 American Association of Cancer Research Annual Meeting 2Trubion Presents Preclinical Data on Its SCORPION(TM) Multispecific Therapeutics at the 2009 American Association of Cancer Research Annual Meeting 3Trubion Presents Preclinical Data on Its SCORPION(TM) Multispecific Therapeutics at the 2009 American Association of Cancer Research Annual Meeting 4Setting the Benchmark for Winery Tasting Room Research: An Emerging Region Gets a Global Perspective 2
(Date:4/27/2015)... , April 27, 2015  For more than ... trade show has been the premier worldwide event for ... 2015 is a must-attend event for any local, national, ... into the emerging commercial markets and current applications of ... innovations of this projected $48 billion industry, and how ...
(Date:4/27/2015)... , Apr. 27, 2015 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market, ... to pre-order customers the first week of May, 2015 ... month of May. Gino Pereira ... milestone for the company as Wocket® enters the consumer ...
(Date:4/27/2015)... FORT LAUDERDALE, Fla. , Apr. 27, 2015 /PRNewswire/ ... provider of access control and security systems is pleased ... joined the company as a consultant and member of ... Bedore is widely known as a thought leader ... Socrates Distance Learning Technology Group, and has published studies ...
Breaking Biology News(10 mins):UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4
... 2010) Healthy pre-and post-menopausal Japanese women who ... a novel soy germ-based ingredient under development for ... reproductive hormones that stayed within normal limits throughout ... at the American Medical Women,s Association (AMWA) 2010 ...
... inhabited the southern coast of Scandinavia 4,000 years ago ... new study carried out by researchers at Uppsala University ... in the journal BMC Evolutionary Biology , supports ... descended from the Stone Age people in question but ...
... of the zebra finch genome, a new resource has ... thematic series published by BioMed Central, the open access ... As part of the series, a study published in ... related to steroid receptors and estrogen biosynthesis. Researchers writing ...
Cached Biology News:Soy germ-based supplement SE5-OH containing natural S-Equol examined for safety, hormonal influence 2Soy germ-based supplement SE5-OH containing natural S-Equol examined for safety, hormonal influence 3Soy germ-based supplement SE5-OH containing natural S-Equol examined for safety, hormonal influence 4Stone Age Scandinavians unable to digest milk 2
Request Info...
Request Info...
Prepared by multi-temperature ethanol fractionation with extensive charcoal treatment and dialysis.• Assay: ≥ 95 % (HPCE)• pH ~5.2 (10 mg/mL in 0.15 M NaCl)...
Special grade: for electrophoresis...
Biology Products: