Over the course of the study, 512 cases of Early AMD were found in 2379 participants who were at risk, and 117 cases of Late AMD were found in 3132 participants that were at risk. Of those participants who used aspirin regularly 10 years prior to their exam, 1.76% showed Late AMD while non-aspirin users showed only a 1.03% incidence. Those with regular aspirin use 10 years prior had an increased incidence of Neovascular AMD but not Pure Geographic Atrophy. There was no effect on the incidence of Early AMD among those who had regularly used aspirin 5 or 10 years previous to their exam.
Klein and her fellow researchers state: “Our findings are consistent with a small but statistically significant association between regular aspirin use and incidence of Neovascular AMD.” This “small association” works out to a 71% overall increased incidence in macular degeneration.
More startling were the results of the research team led by Gerald Liew at the Center for Vision Research, Westmead Millennium Institute for Medical Research, at the University of Sydney (Australia). They published a paper titled: The Association of Aspirin Use With Age-Related Macular Degeneration in the February 2013 issue of the Journal of the American Medical Association Internal Medicine.
Liew and associates conducted a prospective analysis of data from the Blue Mountains Eye Study in Austr
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