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SEATTLE, Aug. 23 /PRNewswire/ -- Amnis Corporation announced today the release of two major upgrades to its ImageStream system including the Commercial release of a multilaser capability and the Beta release of a new technology for dramatically extending the depth of field well beyond conventional optical limitations.
The Multilaser upgrade provides the customer with the flexibility of adding two additional lasers including a 405nm (violet) laser and a 658nm (red) laser. These lasers provide for increased experimental flexibility and sophistication by greatly expanding the fluorescent dye selection available to the customer. The upgrade is accompanied by a novel enhancement to the optical system which provides precise chromatic correction for lower wavelength dyes excited by the 405nm laser. The enhancement enables high resolution imagery resulting from fluorescence excitation from all three lasers to be captured simultaneously across the entire visible spectrum. Customers who purchase the 405nm laser can now perform cell cycle, mitotic analysis and other experiments incorporating the widely-used DNA binding dyes DAPI and Hoechst. The 658nm red laser provides similar advantages for a broad range of red fluorescent dyes. The laser options have been designed for field-based installation and are currently being installed at existing customer sites throughout the world. New instruments are also being shipped per customer order with one, two or all three lasers installed.
The Extended Depth of Field (EDF) upgrade, currently in Beta testing at
seven customer sites, has demonstrated up to a 10 fold increase depth of
field allowing cellular structures to be imaged in crisp focus at positions
well beyond the limitations of conventional imaging techniques. The EDF
technology employs a Wavefront Coded(TM) optical element, developed by CDM
Optics of Boulder, Colorado, operating in concert with rapid optical
deconvolution algorithms developed by Amnis Corporat
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