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Amicus Therapeutics Announces Fourth Quarter and Full Year 2007 Financial Results & Program Advancements
Date:1/29/2008

608) (676) (5,284)

Depreciation and amortization (313) (313)

Interest income 1,789 1,789

Interest expense (79) (79)

Summary:

Net loss: $(10,662) $- $ (1,111) $ (11,773)

Net loss per share - basic

and diluted: $(0.48) $- $(0.05) $(0.53)

Weighted average number of

shares outstanding: 22,343,974 22,343,974

Table 3

Amicus Therapeutics, Inc.

Reconciliation of GAAP to non-GAAP Measures for the
Statement of Operations Information for Three Months Ended December 31, 2006
(Unaudited)

(In thousands, except share and per share amounts)

Change

in Fair

Value

of Preferred

Warrant Stock Stock GAAP as

Non-GAAP Liability Accretion Compensation Reported

Income Statement

Classifications:

Research and

development $ (13,609) $- $- $(577) $(14,186)

General and

administrative (3,582) (448) (4,030)

Depreciation and

amortization (291) (291)

Interest income 786 786

Interest expense (73) (73)

Change in fair value of

warrant liability - 4 4

Preferred stock accretion - (37) (37)

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SOURCE Amicus Therapeutics
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