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Amgen's Third Quarter 2008 Adjusted Earnings Per Share Increased 14 Percent to $1.23
Date:10/22/2008

Nine months ended Nine months ended

September 30, 2008 September 30, 2007

------------------- -------------------

GAAP "Adjusted" GAAP "Adjusted"

------------------- -------------------

Income (Numerator):

Net income for basic and

diluted EPS $3,235 $3,761 $2,331 $3,716

======= ======= ======= =======

Shares (Denominator):

Weighted-average shares

for basic EPS 1,075 1,075 1,127 1,127

Effect of dilutive

securities 4 3(*) 6 4(*)

------- ------- ------- -------

Weighted-average shares

for diluted EPS 1,079 1,078 1,133 1,131

======= ======= ======= =======

Diluted earnings per share $3.00 $3.49 $2.06 $3.29

======= ======= ======= =======

(*) Dilutive securities used to compute "Adjusted" diluted earnings per

share for the three and nine months ended September 30, 2008 and 2007

were computed exclusive of the methodology used to determine dilutive

securities under SFAS No. 123R.

Amgen Inc.

Product Sales Detail by Product and Geographic Region

(In millions)

(Unaudited)

Three months ended Nine months ended

September 30, September 30,

------------------ -----------------

2008 2007
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SOURCE Amgen
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