Navigation Links
Ambry Genetics Launches First X-Linked Mental Retardation Diagnostics Using Next Generation Sequencing

ALISO VIEJO, Calif., March 23 /PRNewswire/ -- Ambry Genetics today introduced The Ambry X-Linked Mental Retardation SuperPANEL™, a suite of genetic tests expected to pinpoint the cause of intellectual disability and X-linked mental retardation (XLMR).  This panel marks the first time next generation sequencing technology, coupled with microarrays, Sanger sequencing and traditional Fragile X testing, is being made clinically available to address this disorder, giving physicians a full range of reflex options to suit the needs of their patients.


The Ambry XLMR SuperPANEL spans all levels of genetic resolution, from genome-wide scan through focused study of the X chromosome to base-pair analysis of approximately ninety specific target genes.  Components include the XLMR Array Plus™, the XLMR Next Gen Sequencing Panel, and individual sequencing tests including Fragile X.  Testing can be customized for individual patients.  The Sequencing Panel uses new and innovative technologies, including RainDance Technologies' RDT 1000 system for sequence enrichment with the Illumina Genome Analyzer IIx.  Ambry has been an Illumina Certified Service Provider for research services since 2007.

"I'm very excited about the various technologies we applied to this suite of tests, and that we can develop similar tests for other complex disease states," said Anja Kammesheidt, Chief Scientific Officer at Ambry Genetics. "The new technologies create an important paradigm shift and allow us to comprehensively investigate complex genetic disorders in the same way monogenic disorders have been diagnosed for years."

"Ambry Genetics is ideally suited to bring multigenic assays into the marketplace," said Charles Dunlop, Chief Executive Officer.  "We've not only been performing services on these platforms for years with a very good understanding of the nuances of these technologies, but we also have over a decade of experience launching high information-content sequencing tests.  We know how to deal with the interpretation issues that arise at the patient level, and our company is geared towards helping physicians with this type of information."

About Ambry Genetics

Ambry Genetics is a CAP-accredited, CLIA-certified commercial clinical laboratory headquartered in Aliso Viejo, California. Established in 2000, it is a recognized leader in diagnostic and contract genomic services.  Ambry specializes in the application of new technologies to molecular diagnostics and genetics research. To learn more, visit

About Intellectual Disability and X-Linked Mental Retardation

Intellectual disability (also called mental retardation) is a lifelong impairment of cognitive and adaptive skills affecting approximately 2-3% of the general population.  For approximately half of patients who have undergone extensive traditional evaluations, the cause remains unknown.  About 10-15% of intellectual disability is attributed to genetic defects of the X chromosome and is called X-linked mental retardation (XLMR).  XLMR affects as many as 1/1000 to 1/600 males plus a significant number of females.  Extensive information about intellectual disability is available from the American Association on Intellectual and Developmental Disabilities at

SOURCE Ambry Genetics

Back to top



SOURCE Ambry Genetics
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Ambry Genetics Announces Certified Service Provider Status for Agilent Microarrays
2. Ambry Genetics Announces the Addition of Array CGH Services Through Partnership With Baylor College of Medicine
3. DuPont to Expand Plant Genetics Research Facilities
4. Interleukin Genetics to Present at the 12th Annual BIO CEO Conference
5. Molecular Genetics Core Facility at Childrens Hospital Boston Selects HybSelect from febit for Targeted Resequencing
6. deCODE genetics, Inc. Announces Approval of First Day Motions by Bankruptcy Court
7. New Appointments at London Genetics to Drive Strategy Forward
8. Viral Genetics Lead Scientist Dr. M. Karen Newell Will Present at 11th Annual SoCalBio Investor and Partnership Conference
9. The Debiopharm Life Sciences Award Goes to Dr Lluis Quintana-Murci for his Novel and Original Research on the Human Evolutionary Genetics of Infection
10. Viral Genetics Responds to Rumors of Imminent FDA Filing and Third Party Press Releases
11. Interleukin Genetics Reports Second Quarter 2009 Financial Results
Post Your Comments:
(Date:6/27/2016)... ... June 27, 2016 , ... Parallel 6 , the leading software as ... Clinical Reach Virtual Patient Encounter CONSULT module which enables both audio and video ... trial team. , Using the CONSULT module, patients and physicians can schedule a face ...
(Date:6/27/2016)... , June 27, 2016  Liquid Biotech ... the funding of a Sponsored Research Agreement with ... tumor cells (CTCs) from cancer patients.  The funding ... CTC levels correlate with clinical outcomes in cancer ... data will then be employed to support the ...
(Date:6/24/2016)... SAN DIEGO , June 24, 2016 /PRNewswire/ ... that more sensitively detects cancers susceptible to PARP ... individual circulating tumor cells (CTCs). The new test ... of HRD-targeted therapeutics in multiple cancer types. ... therapies targeting DNA damage response pathways, including PARP, ...
(Date:6/23/2016)... ... June 23, 2016 , ... Mosio, a leader ... “Clinical Trials Patient Recruitment and Retention Tips.” Partnering with experienced clinical research professionals, ... providing practical tips, tools, and strategies for clinical researchers. , “The landscape of ...
Breaking Biology Technology:
(Date:6/22/2016)... 2016   Acuant , the leading ... has partnered with RightCrowd ® to ... Management, Self-Service Kiosks and Continuous Workforce Assurance. ... functional enhancements to existing physical access control ... with an automated ID verification and authentication ...
(Date:6/15/2016)... ALBANY, New York , June 15, 2016 ... published a new market report titled "Gesture Recognition Market ... Trends and Forecast, 2016 - 2024". According to the ... at USD 11.60 billion in 2015 and is ... and reach USD 48.56 billion by 2024.  ...
(Date:6/2/2016)... The Department of Transport Management (DOTM) ... million US Dollar project, for the , Supply ... Enrolment, and IT Infrastructure , to ... implementation of Identity Management Solutions. Numerous renowned international vendors participated ... was selected for the most compliant and innovative ...
Breaking Biology News(10 mins):