ALISO VIEJO, Calif., May 5 /PRNewswire/ -- Ambry Genetics Corp. announces the implementation of Comparative Genomic Hybridization (CGH) using oligonucleotide arrays through a partnership with
Ambry's CSO, Anja Kammesheidt states, "The oligonucleotide array was developed at
The recent advancements in DNA microarrays are revolutionizing diagnostics by providing the ability to perform targeted and genome-wide studies (GWAS). Array CGH is used to detect genome-wide chromosomal imbalances with a single laboratory test consisting of multiple probes targeting virtually all disorders detected by traditional cytogenetics and fluorescent in situ hybridization (FISH). Array CGH is designed for patients with unexplained developmental delay, autism spectrum disorders, dysmorphic features, unexplained mental retardation, and/or multiple congenital anomalies. Each array contains 105K oligonucleotide probes, spaced at 30K through the genome with increased density at disease loci. Abnormalities are confirmed with other methods such as traditional FISH or MLPA. The test offers high resolution, sensitivity, enhanced clinical detection rates, and greater accuracy in interpretation because of high coverage of clinically significant areas.
About Ambry Genetics
Ambry Genetics is a CAP-accredited, CLIA-certified commercial clinical laboratory headquartered in Aliso Viejo, California. Since the company's inception in 2000, it has become a leader in providing genetic services focused on clinical diagnostics, pharmacogenomics and research support. Ambry has built a solid reputation for unparalleled service, and has been at the forefront of applying new technologies to the clinical molecular diagnostics market and advancements in disease research. To learn more about testing and services available through Ambry, visit www.ambrygen.com.
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|SOURCE Ambry Genetics Corp.|
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